A Novel Chip Device Based on Wired Capillary Packed with High Performance Polymer-based Monolith for HPLC: Reproducibility in Preparation Processes to Obtain Long Columns

• HOSOYA Ken

  Graduate School of Environmental Studies, Tohoku University

• SAKAMOTO Mari

  Graduate School of Environmental Studies, Tohoku University

• AKAI Kunihiko

  Hitachi Chemical Company

• MORI Tomoko

  Graduate School of Environmental Studies, Tohoku University

• KUBO Takuya

  Graduate School of Environmental Studies, Tohoku University

• KAYA Kunimitsu

  Graduate School of Environmental Studies, Tohoku University

• OKADA Kazuma

  Graduate School of Science & Technology, Kyoto Institute of Technology

• TSUJIOKA Norio

  Graduate School of Science & Technology, Kyoto Institute of Technology

• TANAKA Nobuo

  Graduate School of Science & Technology, Kyoto Institute of Technology

抄録

This report describes the development of novel wired chip devices for μ-HPLC analyses. The monolithic capillary column to be wired was prepared using a tri-functional epoxy monomer, tris(2,3-epoxypropyl)isocyanurate with a diamine, 4-[(4-aminocyclohexyl)methyl]cyclohexylamine. The prepared column was evaluated by SEM observation of the sectional structure of column and μ-HPLC. In addition, the reproducibility in the preparation of long capillary columns having nearly 1 m length was extensively examined for applications of novel wired chip devices. The authors demonstrated that the monolithic structure of the prepared long capillary could be finely controlled under the strictly maintained operational conditions and thus the relative standard deviation (RSD) of the column properties such as the number of theoretical plates, retention factor, and permeability could be well controlled to become less than 10%. Furthermore, the wired chip device column showed that its high performance was kept even after chip preparation.

収録刊行物

• Analytical Sciences

  Analytical Sciences 24 (1), 149-154, 2008

  社団法人 日本分析化学会

キーワード

• Analytical Chemistry

詳細情報

• CRID: 1390001204255313792
• NII論文ID: 130004441557
• NII論文ID: 10020143775
• NII書誌ID: AA10500785
• DOI: 10.2116/analsci.24.149
• ISSN: 13482246
• ISSN: 09106340
• NDL書誌ID: 9326923
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9326923
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.24.149.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.24.149/fulltext.html
• Web Site: http://www.jstage.jst.go.jp/article/analsci/24/1/24_1_149/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可