肝細胞癌,胆管癌,胆嚢癌の診断における[18F]FDG-PETの臨床的有用性-多施設アンケート調査による検討-

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  • Clinical Usefulness of [18F] FDG-PET for Diagnosis of Hepatocellular Carcinoma, Cholangiocarcinoma and Gall Bladder Carcinoma—An Analysis Based on Multi-center Questionnaire Survey—
  • カンサイボウ ガン タンカン ガン タンノウ ガン ノ シンダン ニ オケル 18F FDG PET ノ リンショウテキ ユウヨウセイ タシセツ アンケート チョウサ ニ ヨル ケントウ

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To evaluate the clinical usefulness of FDG-PET in the diagnosis of hepatocellular carcinima (HCC), cholangiocellular carcinoma (CCC), and gall bladder carcinoma (GBC), we performed multi-institutional questionnaire survey about the current status of diagnostic FDG-PET study for these tumors in Japan. The questionnaire was performed on individual-patient-basis, and the questionnaire items were the following; age, sex, the purpose of the study, assertion about the clinical usefulness of the study, and its reasons. Forty-two cases of HCC (male:33 cases, age:59.1±14.8, female:9 cases, age:69.8±6.2), fifty-one cases of CCC (male:37 cases, age:65.0±9.9, female:14 cases, age:67.9±6.2), and twenty cases of GBC (male:11 cases, age:66.5±8.4, female:9 cases, age:71.7±12.0). Clinical usefulness was evaluated as highly-useful (HU), useful (U), and not useful (NU) in each case in each group for A) initial diagnosis or for B) staging, recurrence, or treatment decision. Clinical usefulness was asserted as effective in all groups (HCC:A) HU/U/NU:4/0/2cases, B) HU/U/NU:30/7/2cases;CCC:A) HU/U/NU:11/9/5cases, B) HU/U/NU:21/17/5cases;GBC:A) HU/U/NU:6/2/2cases, B) HU/U/NU:10/3/1cases.) According to this survey, the clinical diagnosis of FDG-PET was useful in the diagnosis of hepatocellular carcinima, cholangiocellular carcinoma, and gall bladder carcinoma, for initial diagnosis or for staging, recurrence, or treatment decision.

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