Two cases of pyogenic spondylitis with chronic hepatitis C during combination therapy of interferon alfa and ribavirin

  • SUGAHARA Kazuhiko
    Department of Gastroenterology, Yamagata University School of Medicine
  • SAITO Takafumi
    Department of Gastroenterology, Yamagata University School of Medicine
  • WATANABE Hisayoshi
    Department of Gastroenterology, Yamagata University School of Medicine
  • MISAWA Keiko
    Department of Gastroenterology, Yamagata University School of Medicine
  • ISHII Rika
    Department of Gastroenterology, Yamagata University School of Medicine
  • SUZUKI Akihiko
    Department of Gastroenterology, Yamagata University School of Medicine
  • HAGA Hiroaki
    Department of Gastroenterology, Yamagata University School of Medicine
  • SANJO Mai
    Department of Gastroenterology, Yamagata University School of Medicine
  • OKUMOTO Kazuo
    Department of Gastroenterology, Yamagata University School of Medicine
  • NISHISE Yuko
    Department of Gastroenterology, Yamagata University School of Medicine
  • ITO Junitsu
    Department of Gastroenterology, Yamagata University School of Medicine
  • SAITO Koji
    Department of Gastroenterology, Yamagata University School of Medicine
  • TOGASHI Hitoshi
    Health administration center, Yamagata University School of Medicine
  • KAWATA Sumio
    Department of Gastroenterology, Yamagata University School of Medicine

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Other Title
  • インターフェロン·リバビリン併用療法中に化膿性脊椎炎を 合併したC型慢性肝炎の2例

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Abstract

This report describes our experience with two cases of pyogenic spondylitis with chronic hepatitis C during combination therapy of interferon alfa and ribavirin. The first patient, a 59-year-old man, was treated conservatively and improved, but the second patient, a 69-year-old woman, was not improved by conservative therapy and reconstructive operation was performed. The combination therapy of interferon alfa and ribavirin has a high risk of severe infectious diseases as side effects. CT scan and MRI are recommended immediately to diagnose pyogenic spondylitis, when patients has pyrexia and lumbago with laboratory data suspected inflammation during interferon therapy.<br>

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