Synthesis and Photocleavage of 7-[{Bis(carboxymethyl)amino}-coumarin-4-yl]methyl-Caged Neurotransmitters
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- Senda Naoko SENDA Naoko
- Graduate School of Pure and Applied Sciences, University of Tsukuba
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- Momotake Atsuya MOMOTAKE Atsuya
- Graduate School of Pure and Applied Sciences, University of Tsukuba
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- Arai Tatsuo ARAI Tatsuo
- Graduate School of Pure and Applied Sciences, University of Tsukuba
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Author(s)
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- Senda Naoko SENDA Naoko
- Graduate School of Pure and Applied Sciences, University of Tsukuba
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- Momotake Atsuya MOMOTAKE Atsuya
- Graduate School of Pure and Applied Sciences, University of Tsukuba
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- Arai Tatsuo ARAI Tatsuo
- Graduate School of Pure and Applied Sciences, University of Tsukuba
Abstract
7-[{Bis(carboxymethyl)amino}coumarin-4-yl]methyl-caged neurotransmitters (glutamate and GABA) were synthesized. Both caged compounds showed sufficient stability in the dark, were water-soluble at pH 7.2 without using organic solvents, and exhibited relatively high quantum yield for photolysis upon irradiation with 390 nm light.
Journal
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- Bulletin of the Chemical Society of Japan
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Bulletin of the Chemical Society of Japan 80(12), 2384-2388, 2007-12-15
The Chemical Society of Japan
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