A case of <i>H. pylori</i> and API2-MALT1 gene-negative gastric mucosa-associatedlymphoid tissue lymphoma with a carcinoma-like signet-ring celllymphoepithelial lesion

  • SUMIDA Tomonori
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • NAGATA Shinji
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • OHGOSHI Hiroaki
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • ISHIDA Yuki
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • KUWABARA Takayasu
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • TSUMURA Takako
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • TSUJI Keiji
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • HIDAKA Tohru
    Department of Internal Medicine and Endoscopy, Hiroshima City Asa Hospital
  • KANEKO Mayumi
    Department of Pathology, Hiroshima City Asa Hospital
  • YOSHINO Tadashi
    Department of Pathology, Okayama University Graduate School of Medicine

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  • 放射線療法が奏功した<i>H. pylori</i>およびAPI2-MALT1遺伝子陰性胃MALTリンパ腫の1例

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Abstract

A 60-year-old woman presented in February 2003 with an ulcer on the lesser curvature of the anglus. The endoscopic biopsy specimens showed epithelial signet-ring cell associated with lymphoid infiltration, suggesting a diagnosis of gastric cancer. Histopathological examination confirmed the diagnosis of low-grade B-cell lymphoma of MALT with epithelial signet-ring cell lymphoepithelial lesion, which was negative for H. pylori and t (11;18) (q21;q21) translocation (API2-MALT1 gene) D This case was treated with H. pylori eradication and additional radiation therapy, and the tumor was disappeared.<br>

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