ワルファリンカリウム服用中患者の抜歯時の服薬調整による血栓形成のリスク期間について

• 井上 育子

  Department of Dentistry and Oral Surgery, School of Medicine, Fukuoka University

• 梅本 丈二

  Department of Dentistry and Oral Surgery, School of Medicine, Fukuoka University

• 穐山 靖子

  Department of Dentistry and Oral Surgery, School of Medicine, Fukuoka University

• 喜久田 利弘

  Department of Dentistry and Oral Surgery, School of Medicine, Fukuoka University

書誌事項

タイトル別名

• The existence of thromboembolism risks by altering warfarin potassium administration prior to dental extractions

抄録

In patients receiving warfarin potassium anticoagulant therapy, alteration of warfarin potassium administration prior to and following dental extractions increases the risk of thromboembolisms. We investigated if there exist the risk of thromboembolisms due to alteration of warfarin administration by evaluating the changes of PT-INR (prothrombin time international normalized ratio) prior to and following dental extractions.<BR>Subjects enrolled in this study were 83 warfarinised patients that required dental extractions from January 1, 1996 to December 31, 2004 (Maintained group: 25, Reduced group: 11, Reduced and interrupted group: 4, Interrupted group: 35, Heparinized group: 8).<BR>Our study findings suggested that the four groups with the exception of the Maintained group have a risk of thromboembolisms for 7.5 days. In the Maintained group, on case was difficult to attain hemostasis after dental extraction. Therefore, our study findings are suggestive that dental extractions under maintenance doses are possible for cases requiring non-complicated dental extractions if the PT-INR is 3.0 or less.

収録刊行物

• 有病者歯科医療

  有病者歯科医療 15 (2), 67-72, 2006

  一般社団法人 日本有病者歯科医療学会

詳細情報

• CRID: 1390001204486404736
• NII論文ID: 10020366220
• NII書誌ID: AN10401297
• DOI: 10.11255/jjmcp1992.15.67
• ISSN: 1884667X
• ISSN: 09188150
• Web Site: https://search.jamas.or.jp/link/ui/2007211409
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可