高圧下へのタンパク質の適応

• 加藤 千明

  独立行政法人海洋研究開発機構 極限環境生物圏研究センター

書誌事項

タイトル別名

• Protein Adaptation to High-Pressure Environments
• コウアツカ エノ タンパクシツ ノ テキオウ

抄録

Studies of pressure-adapted (piezophilic) protein have lagged behind the investigation of other extremophilic proteins, however the recent characterization of proteins from deep-sea organisms has substantially accelerated the field. Recent experiments on proteins from deep-sea sources have contributed to our understanding of protein adaptation to high pressure. These studies have also complemented previous work that had investigated the effect of pressure on the activity and stability of “normal”, unadapted proteins. Together this research has lead to the conclusion that volume changes due to the hydration effects of exposed side chains and large internal cavities drive protein unfolding under high pressure.

収録刊行物

• 高圧力の科学と技術

  高圧力の科学と技術 18 (2), 128-132, 2008

  日本高圧力学会

キーワード

• deep-sea
• enzyme activity
• piezophilic
• protein structure
• Shewanella violacea

詳細情報

• CRID: 1390001204380951040
• NII論文ID: 10021153494
• NII書誌ID: AN10452913
• DOI: 10.4131/jshpreview.18.128
• ISSN: 13481940
• ISSN: 0917639X
• NDL書誌ID: 9536453
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9536453
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可