Highly Enantioselective X-H (X=N, O) Insertion Reactions by Metal Complexes

• Saito Hiroaki

Bibliographic Information

Other Title

• 金属錯体による高エナンチオ選択的Ｘ‐Ｈ（Ｘ＝Ｎ，Ｏ）挿入反応

Abstract

The catalytic insertion of a-diazo compounds into C-H or X-H (X = heteroatom) bonds is a very powerful organic transformation, due to the potential in forming highly versatile building blocks. Remarkable advances have been made in the methodology for catalytic asymmetric diazo insertion into C-H bond, but only limited success has been achieved for asymmetric insertions into X-H bonds. Recently, high levels of enantiocontrol in the asymmetric X-H insertions have been achieved by the device of well-defined chiral Cu complexes. In this short review, several recent examples of catalytic asymmetric N-H and 0-H insertions are introduced.

Journal

• Journal of Synthetic Organic Chemistry, Japan

  Journal of Synthetic Organic Chemistry, Japan 66 (7), 714-715, 2008

  The Society of Synthetic Organic Chemistry, Japan

Keywords

• The catalytic insertion of a-diazo compounds into C-H or X-H (X = heteroatom) bonds is a very powerful organic transformation, due to the potential in forming highly versatile building blocks. Remarkable advances have been made in the methodology for catalytic asymmetric diazo insertion into C-H bond, but only limited success has been achieved for asymmetric insertions into X-H bonds. Recently, high levels of enantiocontrol in the asymmetric X-H insertions have been achieved by the device of well-defined chiral Cu complexes. In this short review, several recent examples of catalytic asymmetric N-H and O-H insertions are introduced.

Details

• CRID: 1390282680288573184
• NII Article ID: 10021176202
• NII Book ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.66.714
• ISSN: 18836526
• ISSN: 00379980
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed