低音障害型感音難聴 : 内耳自己抗体陽性一症例の治療経過  [in Japanese] A case of low tone sensory nerve hearing loss with positive inner ear autoantibodies  [in Japanese]

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Author(s)

    • 富山 俊一 TOMIYAMA Shunichi
    • 日本医科大学多摩永山病院耳鼻咽喉科 Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital
    • 斉藤 明彦 SAITOU Akihiko
    • 日本医科大学多摩永山病院耳鼻咽喉科 Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital
    • 野中 学 NONAKA Manabu
    • 日本医科大学多摩永山病院耳鼻咽喉科 Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital

Abstract

A case of acute low tone sensory nerve hearing loss with positive 68kDa inner ear autoantibody was reported. Prednisone 60mg administration and tapering was effective shortly. Fourth relapse of hearing loss occurred shortly after hearing recovery during steroid tapering.<BR>Then, combined therapy of cyclophosphamide and prednisone was initiated Hearing loss was completely recovered and normal hearing has been maintained for over 18 months. Consequently, it was suggested that autoimmune pathogenesis played an important role in this lowtone sensory nerve hearing loss.

Journal

  • Otology Japan

    Otology Japan 17(1), 26-32, 2007-02-25

    THE JAPAN OTOLOGICAL SOCIETY

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