A case of low tone sensory nerve hearing loss with positive inner ear autoantibodies

• Tomiyama Shunichi

  Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital

• Saitou Akihiko

  Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital

• Nonaka Manabu

  Department of Otorhinolaryngology, Nippon Medical School, Tama-Nagayama Hospital

Bibliographic Information

Other Title

• 低音障害型感音難聴―内耳自己抗体陽性一症例の治療経過―
• 内耳自己抗体陽性一症例の治療経過

Abstract

A case of acute low tone sensory nerve hearing loss with positive 68kDa inner ear autoantibody was reported. Prednisone 60mg administration and tapering was effective shortly. Fourth relapse of hearing loss occurred shortly after hearing recovery during steroid tapering.<BR>Then, combined therapy of cyclophosphamide and prednisone was initiated Hearing loss was completely recovered and normal hearing has been maintained for over 18 months. Consequently, it was suggested that autoimmune pathogenesis played an important role in this lowtone sensory nerve hearing loss.

Journal

• Otology Japan

  Otology Japan 17 (1), 26-32, 2007

  Japan Otological Society

Keywords

• inner ear
• autoimmune
• autoantibodies
• low tone sensory nerve hearing loss
• immunosuppressant

Details

• CRID: 1390282679746477184
• NII Article ID: 10021297986
• NII Book ID: AN10358085
• DOI: 10.11289/otoljpn1991.17.26
• ISSN: 18841457
• ISSN: 09172025
• Web Site: https://search.jamas.or.jp/link/ui/2007294908
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed