Breakdown of the Blood-labyrinth Barrier in Sensorineural hearing loss

  • Yoshida Tadao
    Department of Otorhinolaryngology Nagoya University Graduate School of Medicine
  • Sugiura Makoto
    Department of Otorhinolaryngology Nagoya University Graduate School of Medicine
  • Teranishi Masaaki
    Department of Otorhinolaryngology Nagoya University Graduate School of Medicine
  • Nakata Seiichi
    Department of Otorhinolaryngology Nagoya University Graduate School of Medicine
  • Nakashima Tsutomu
    Department of Otorhinolaryngology Nagoya University Graduate School of Medicine

Bibliographic Information

Other Title
  • 内耳性難聴における血液迷路関門の破綻症例について

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Abstract

Three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) MRI has recently been used to evaluate the pathology of the inner ear in cases of sensorineural hearing loss (SNHL). It is also possible by this method to detect the breakdown of the blood-labyrinth barrier in the affected ears. In this study, nine of twelve patients with sudden SNHL showed high signals in the affected ear on precontrast 3D-FLAIR. Two of these patients also showed gadolinium enhancement on 3D-FLAIR in the affected inner ear. Furthermore, the patient with acute [as different from “sudden”?] SNHL also showed gadolinium enhancement in the affected inner ear. This finding suggests a breakdown of the blood-labyrinth barrier at the time of the MRI. Further study is required to clarify the relationship between the 3D-FLAIR findings and the hearing prognosis. It is expected that 3D-FLAIR MRI would be useful for elucidating the pathologic condition in cases of SNHL.

Journal

  • AUDIOLOGY JAPAN

    AUDIOLOGY JAPAN 50 (2), 157-162, 2007

    Japan Audiological Society

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