Three Cases of Gangrenous Ischemic Colitis Who Were Saved by Colectomy

  • Tagami S.
    Department of Gastrointestinal and General Surgery, Kawakita General Hospital
  • Sato Y.
    Department of Gastrointestinal and General Surgery, Kawakita General Hospital
  • Murata Y.
    Department of Gastrointestinal and General Surgery, Kawakita General Hospital
  • Hattori S.
    Department of Gastrointestinal and General Surgery, Kawakita General Hospital
  • Sunouchi K.
    Department of Gastrointestinal and General Surgery, Kawakita General Hospital

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Other Title
  • 救命しえた壊死型虚血性大腸炎の3例

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Abstract

Patients with ischemic colitis are usually treated conservatively; however, those who develop gangrene as a result require surgical intervention. The causes of gangrenous ischemic colitis have not yet been clearly identified, although much evidence has been accumulated to suggest that vessel disease and intestinal injury are closely involved.<br> We encountered three cases of gangrenous ischemic colitis and investigated the differences in the clinicopathologic characteristics between our cases and cases with non-occlusive mesenteric ischemia (NOMI). The areas affected by ischemic damage in our cases were limited to the left side of the colon. Colectomy was performed at 30, 70, and 60 hours after onset in each case. The bowel infarction was suspected to be precipitated by trauma and colonic bacteria in the first case, atherosclerotic disease of the arteries supplying the bowel with constipation and bacteria in the second case and chronic segmental colitis with constipation in the third case.<br> In the cases with NOMI, the mesenteric perfusion may be compromised because of vessel spasm in hemodynamically unstable patients, such as heart disease. Useful diagnostic criteria for gangrenous ischemic colitis need to be established to devise appropriate strategies for therapy, and to determine the survival rates and quality of life of these patients.<br>

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