Clinicopathological Study of Mixed Tumor of the Skin

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  • 皮膚混合腫瘍（mixed tumor of the skin）の臨床病理学的検討
  • ヒフ コンゴウ シュヨウ mixed tumor of the skin ノ リンショウ ビョウリガクテキ ケントウ

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Abstract

We performed a clinicopathological study of mixed tumor of the skin (MTS) in 130 cases. These included 78 male and 52 female cases ; the average age at resection was 54.6 years. Most cases arose on the face (119 cases: 92%). Histopathological examination revealed that the apocrine type of MTS contains glandular structures with decapitation secretion and ductal structures consisting of poroid and cuticular cells. We comfirmed the histopathological findings as follows: 1) 126 cases (97%) were apocrine type and only 4 cases (3%) were eccrine type, 2) cells with myoepithelial differenatiation (plasmacytoid cells), were observed in 114 cases (88%), 3) keratinous cysts were observed in 61 cases (47%), and aggregations of follicular germinative cells were seen in 54 cases (42%), 4) sebaceous differentiation was seen in 5 cases (4%), 5) connection to the epidermis was confirmed in 9 cases (7%), 6) the solid portion occupied a large area, in 55 cases (42%) and a solid portion was not confirmed in 8 cases (6%), 7) myxoid change were seen in 125 cases (96%), chondroid changes, in 43 cases (33%), osteoid changes, in 11 cases (8%), and adipotic changes, in 46 cases (35%).

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