Effects of Type of Diet and Salinomycin Supplementation on Insulin Secretory Response and Action in Sheep
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- FUJITA Tadahisa
- Faculty of Agriculture, Iwate University
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- ITOH Takahiro
- Faculty of Agriculture, Iwate University
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- MAJIMA Hiroya
- Faculty of Agriculture, Iwate University
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- SANO Hiroaki
- Faculty of Agriculture, Iwate University
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- SHIGA Akio
- Faculty of Agriculture, Iwate University
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- AMBO Kaichi
- Faculty of Agriculture, Iwate University
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Abstract
Hyperglycemic clamp and hyperinsulinemic euglycemic clamp techniques were used to investigate the effects of type of diet and salinomycin supplementation on the insulin secretory response to glucose and tissue responsiveness to insulin in adult sheep. The sheep were fed a high-roughage and a high-concentrate diet at equal energy intakes with or without 20ppm of salinomycin for 3 weeks. Basal plasma glucose concentrations were unaffected by type of diet or salinomycin supplementation in both glucose clamp experiments. The ratio of plasma insulin increments to glucose infusion rates in the hyperglycemic clamp experiment and the glucose infusion rate in the hyperinsulinemic euglycemic clamp experiment were unaffected by type of diet or salinomycin supplementation. Although the number of data was small in the present study, these results suggest that in sheep salinomycin supplementation has no significant effects on either the insulin secretory response to glucose or on insulin action, regardless of type of diet.
Journal
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- Nihon Chikusan Gakkaiho
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Nihon Chikusan Gakkaiho 71 (1), 42-49, 2000
Japanese Society of Animal Science
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Keywords
Details 詳細情報について
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- CRID
- 1390282680173727360
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- NII Article ID
- 10021722058
- 10020391283
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- NII Book ID
- AN00195188
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- ISSN
- 18808255
- 00215309
- 1346907X
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- NDL BIB ID
- 4970227
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed