Nonlinear Raman Spectroscopic Imaging Using a White-light Light Laser Source

• KANO Hideaki

  Department of Chemistry, School of Science, University of Tokyo PRESTO (Precursory Research for Embryonic Science and Technology), Japan Science and Technology Agency

Bibliographic Information

Other Title

• 白色レーザーを用いた非線形ラマン分光イメージング
• ハクショク レーザー オ モチイタ ヒセンケイ ラマン ブンコウ イメージング

Abstract

Coherent anti-Stokes Raman scattering (CARS) microscopy and microspectroscopy have become powerful techniques for three-dimensional vibrational imaging of chemical and biological systems. Recently, a significant progress has been made of multiplex CARS microspectroscopy, in which a spectral coverage broader than 3500 cm^-1 has been achieved using a white-light laser source. In the present study, we have used a photonic crystal fiber (PCF) to generate a white-light laser and used it as the Stokes light source in the CARS process. Owing to an ultrabroadband spectral profile of the white-light laser, a wide range of the vibrational resonances can be investigated.In the present study, we have performed label-free, multi-color imaging of biological samples using multiplex CARS microspectroscopy.

Journal

• Journal of the Spectroscopical Society of Japan

  Journal of the Spectroscopical Society of Japan 57 (5), 238-248, 2008

  The Spectroscopical Society of Japan

Keywords

• Coherent anti-Stokes Raman Scattering
• CARS
• microscopy
• microspectroscopy
• photonic crystal fiber
• supercontinuum
• white-light laser
• living cell

Details

• CRID: 1390001206258716928
• NII Article ID: 10021874433
• NII Book ID: AN00222531
• DOI: 10.5111/bunkou.57.238
• ISSN: 18846785
• ISSN: 00387002
• NDL BIB ID: 9693276
• Web Site: http://id.ndl.go.jp/bib/9693276
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9693276
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed