微小粒子状物質の生体影響 － 自律神経への影響を測定する －

• 丸山 良子

  東北大学大学院医学系研究科　保健学専攻

書誌事項

タイトル別名

• The Effect of Ambient Particulate Matter on Cardiovascular Responses
• ビショウ リュウシジョウ ブッシツ ノ セイタイ エイキョウ ジリツ シンケイ エノ エイキョウ オ ソクテイスル

抄録

Evidence has been accumulated to show that the particulate matter in polluted air is associated with increased cardiovascular morbidity and mortality. Our studies demonstrated that the effect of single intrataracheal instillation of PM_2.5 in Spontaneous Hypertensive Rat (SHR) decreased the heart rate (HR) and increased the parasympathetic nervous activity. Five hours exposure to PM_2.5 tended to enhance the lung resistance, leading to a decreased in HR and an increase in parasympathetic nervous activity. There were no significant changes in the sympathetic parameter. These results suggest that the cardiac function may play a role in pathogenesis relating to harmful effect of PM_2.5 on SHR. <BR>More comparative study is needed for health effect of PM_2.5, ultrafine particles and nanoparticles.

収録刊行物

• エアロゾル研究

  エアロゾル研究 23 (3), 187-192, 2008

  日本エアロゾル学会

キーワード

• Particulate Matter
• PM<SUB>2.5</SUB>
• Heart Rate Variability
• Heart Rate
• HF

詳細情報

• CRID: 1390282679318956288
• NII論文ID: 10021919204
• NII書誌ID: AN10041511
• DOI: 10.11203/jar.23.187
• ISSN: 1881543X
• ISSN: 09122834
• NDL書誌ID: 9654633
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9654633
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可