A case of advanced hepatocellular carcinoma successfully treated by combined therapies including transarterial chemoembolization using Lipiodol- CDDP powder suspension

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Other Title
  • 粉末シスプラチン動注治療が奏効し集学的治療にて無再発生存中の高度進行肝細胞癌の１例
  • 症例報告 粉末シスプラチン動注治療が奏効し集学的治療にて無再発生存中の高度進行肝細胞癌の1例
  • ショウレイ ホウコク フンマツ シスプラチン ドウチュウ チリョウ ガ ソウコウシ シュウガクテキ チリョウ ニテ ムサイハツ セイゾンチュウ ノ コウド シンコウ カン サイボウ ガン ノ 1レイ

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Abstract

We report a case of advanced multiple hepatocellular carcinomas (HCC), successfully treated by combination therapies of transarterial chemoembolization (TACE), surgical operation and radiofrequency ablation therapy (RFA). The patient was a 60-year-old man, who had been investigated in another hospital for abdominal pain and general fatigue, and was subsequently referred to our hospital with a diagnosis of HCC. A huge tumor with a diameter larger than 10 cm and a set of multiple intrahepatic metastases (IM) to bilateral lobes were recognized. In addition, portal vein tumor thrombosis of the left branch (Vp3) was observed. He received serial treatments with TACE using lipiodol- CDDP powder suspension. After 4 courses of this therapy, CT revealed that these IM tumors had disappeared. Therefore we performed a left hepatic lobectomy. Then he was treated with RFA. He has still been well for 28 months since the first detection of HCC. It was suggested that a TACE using CDDP powder may be one of the most effective treatment modalities against advanced HCC.<br>

Journal

  • Kanzo

    Kanzo 49 (7), 314-319, 2008

    The Japan Society of Hepatology

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