A Case of Black Thyroid Associated with Hyalinizing Trabecular Tumor
-
- KANG Sang-Wook
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- HONG Soon Won
- Department of Pathology, Yonsei University College of Medicine
-
- YEON Pyo Ju
- Department of Pathology, Yonsei University College of Medicine
-
- JEONG Jong Ju
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- SUNG Tae Yon
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- LEE Seung Chul
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- LEE Yong Sang
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- NAM Kee-Hyun
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- CHUNG Woong Youn
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- CHANG Hang Seok
- Thyroid Cancer Clinic, Yonsei University College of Medicine
-
- PARK Cheong Soo
- Thyroid Cancer Clinic, Yonsei University College of Medicine
この論文をさがす
抄録
Black thyroid is an uncommon phenomenon of black pigmentation of thyroid parenchyma induced by chronic minocycline therapy. Thyroid tumors associated with black pigmented thyroid are rare. We describe here a 42-year-old woman with a black thyroid associated with hyalinizing trabecular tumor (HTT). The patient presented with a palpable left-sided thyroid nodule. She had taken minocycline for aphthous stomatitis and an oral ulcer for 9 years. The findings of fine needle aspiration biopsy and BRAF mutation analysis suggested a papillary carcinoma. The patient underwent a near-total thyroidectomy with central compartment node dissection. The surgical specimen showed a diffuse black thyroid and a 2-cm non-pigmented, well-circumscribed nodule in the left thyroid. Histopathologically, numerous black pigmented follicular epithelial cells and colloid were seen throughout the thyroid parenchyma, and the nodule was composed of elongated, polygonal cells in trabecular arrangement and dense hyaline stromas. The tumor cells showed a strong positive cytoplasmic reaction to Ki 67. All of these findings suggested a HTT, or a hyalinizing trabecular variant of papillary carcinoma, arising in a black thyroid. To our knowledge, this is the first case of black thyroid associated with HTT.<br>
収録刊行物
-
- Endocrine Journal
-
Endocrine Journal 55 (6), 1109-1112, 2008
一般社団法人 日本内分泌学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282681275659904
-
- NII論文ID
- 10023973381
- 130004443467
-
- NII書誌ID
- AA10901436
-
- COI
- 1:STN:280:DC%2BD1M%2FkvVWntA%3D%3D
-
- ISSN
- 13484540
- 09188959
-
- PubMed
- 18753707
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可