Possible use of silver ion solution as a disinfectant in hemodialysis
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- Hori Hideo
- Department of Clinical Engineering Technology, Fujita Health University College
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- Ohashi Atsushi
- Department of Clinical Engineering Technology, Fujita Health University College
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- Hibiya Makoto
- Department of Clinical Engineering Technology, Fujita Health University College
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- Nakai Shigeru
- Department of Clinical Engineering Technology, Fujita Health University College
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- Hara Susumu
- Department of Microbiology, Fujita Health University College
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- Hashidume Hideaki
- Department of Blood Purification Center, Fujita Health University Hospital
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- Nii Norio
- Department of Blood Purification Center, Fujita Health University Hospital
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- Kato Masao
- Department of Blood Purification Center, Fujita Health University Hospital
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- Murakami Kazutaka
- Department of Nephrology, Fujita Health University School of Medicine
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- Nabeshima Kunihiro
- Department of Nephrology, Fujita Health University School of Medicine
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- Tomita Makoto
- Department of Nephrology, Fujita Health University School of Medicine
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- Hasegawa Midori
- Department of Nephrology, Fujita Health University School of Medicine
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- Hiki Yoshiyuki
- Department of Nephrology, Fujita Health University School of Medicine
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- Sugiyama Satoshi
- Department of Nephrology, Fujita Health University School of Medicine
Bibliographic Information
- Other Title
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- 透析用消毒剤としての銀イオン水の可能性
- トウセキヨウ ショウドクザイ ト シテノ ギン イオンスイ ノ カノウセイ
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Abstract
Silver is used in various fields because of its high safety and broad antimicrobial spectrum. Here, the bactericidal activities of silver ion (Ag+) solution were compared to those of sodium hypochlorite (NaClO) in order to determine its usefulness as a disinfectant in hemodialysis. The minimum killing concentration (MKC) of each disinfectant was measured using the bacterial strains Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus. With bacteria isolated from product water manufacturing processes (tap water, activated carbon filter treatment water, and RO water) and the dialysis fluid line (B tank and dialysis fluid), antibacterial tests were conducted using each disinfectant. In terms of MKC, while Ag+ solution was not as fast acting as NaClO, comparable bactericidal activities were observed over time. In particular, Ag+ solution appears to be more effective than NaClO in disinfecting chlorine-resistant water-borne bacteria inside the product water manufacturing line. In addition, Ag+ solution killed not only Gram-negative bacteria, but also Gram-positive bacteria. Thus, Ag+ solution may be used as a disinfectant in hemodialysis and it appears to be as useful as NaClO.
Journal
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- Nihon Toseki Igakkai Zasshi
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Nihon Toseki Igakkai Zasshi 41 (11), 771-778, 2008
The Japanese Society for Dialysis Therapy
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Keywords
Details
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- CRID
- 1390282679657042304
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- NII Article ID
- 10023974351
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- NII Book ID
- AN10432053
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- ISSN
- 1883082X
- 13403451
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- NDL BIB ID
- 9739455
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed