幻肢痛に対する大脳皮質刺激療法のメカニズム解析  [in Japanese] Mechanistic analysis of motor cortex stimulation for phantom limb pain  [in Japanese]

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Author(s)

Abstract

   Phantom limb pain and other deafferentation pain are characterized by changes in cortical processing and organization (cortical reorganization), poor response to conventional treatments. Whereas several studies reported a close relationship between imagery movements of the amputated or paralyzed limb and the intractable pain, the alterations in the motor cortex related to the imagery movements has not yet been explored in detail. Here, we studied the electrocorticogram (ECoG) of sensorimotor cortex in deafferentation pain to reveal the relationship between some imagery movement tasks and the dynamical pattern of ECoG during the tasks. A clear correlation between the ECoG and imagery movements was observed in a patient who well responded to motor cortex stimulation (MCS). On the other hand, there was little correlation between them in a patient who did not respond to MCS. For the former patient, the optimal stimulation site for MCS located around the primary motor cortex, where the pattern of ECoG well differentiated among types of imagery movements. We will discuss the relation between imagery movements and the effects of MCS.

Journal

  • PAIN RESEARCH

    PAIN RESEARCH 23(1), 27-34, 2008-01-31

    JAPANESE ASSOCIATION FOR STUDY OF PAIN

References:  17

Codes

  • NII Article ID (NAID)
    10024130730
  • NII NACSIS-CAT ID (NCID)
    AN10195934
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    09158588
  • Data Source
    CJP  J-STAGE 
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