A Case Study on Cardiac Imaging in Patients with Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy-A Comparison between 64-Slice Computed Tomography, Magnetic Resonance Imaging and Electroanatomical Mapping-

  • Nishiyama Kei
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
  • Doi Takahiro
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
  • Shizuta Satoshi
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
  • Yamamoto Takayuki
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
  • Hanazawa Kouji
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
  • Kita Toru
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
  • Kimura Takeshi
    Departments of Cardiovascular Medicine, Kyoto University Graduate School of Medicine

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Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an uncommon type of cardiomyopathy with fibrofatty tissue replacement. Magnetic resonance imaging (MRI) is a sophisticated method for the diagnosis of ARVD/C. Electroanatomical mapping has been reported to rapidly provide accurate data that facilitates catheter ablation of VT in ARVD/C. In addition, multislice CT (MSCT) is fast, easy to perform, and has a more reliable image quality. MSCT is considered a clinically valuable, noninvasive tool for assessment of myocardial pathology. However, the relationship between MSCT, cardiac MRI and electroanatomical mapping imaging in patients with ARVD/C is unknown. We report two cases diagnosed as ARVD/C by endomyocardial biopsy. In one case MRI imaging revealed marked wall thinning and a decrease in wall motion in the inferior wall and basal interventricular septum of the left ventricle. In another case an electroanatomical map of the RV was created. Endocardial voltage mapping in sinus rhythm revealed a large low voltage area and a focal pattern of activation was documented in activation mapping during VT. In both cases MSCT demonstrated low density areas indicative of focal fatty infiltration and morphological and functional abnormalities which were simultaneously assessed with MRI or electroanatomical mapping.

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