Fluorescence bioimaging under near infrared excitation using upconversion in rare-earth-doped ceramic nanophosphors

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  • 希土類含有セラミックスナノ粒子によるアップコンバージョン現象を利用した近赤外励起バイオイメージング
  • キドルイ ガンユウ セラミックス ナノ リュウシ ニ ヨル アップコンバージョン ゲンショウ オ リヨウシタ キンセキガイ レイキ バイオイメージング

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Abstract

<p>Fluorescence bioimaging is one of the most important techniques in biomedical technologies. Current imaging technologies are limited in terms of the time and depth of observation due to the use of short-wavelength excitation light, such as UV or blue light, which causes color fading of the phosphors and photodamage to the substances in the biological system being imaged. Ceramic nanophosphors doped with rare-earth ions are known to emit fluorescence efficiently under near-infrared excitation. The use of near-infrared excitation with the ceramic nanophosphors is expected to solve the above problems caused by short-wavelength excitation light. In this article, the development of a fluorescence bioimaging system using near-infrared excitation using rare-earth-doped ceramic nanophosphors is reported.</p>

Journal

  • Oyo Buturi

    Oyo Buturi 77 (12), 1458-1461, 2008-12-10

    The Japan Society of Applied Physics

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