Capillary-Assembled Microchip: Development of electrophoretic separation systems based on square Capillary-Embedded Microchip.

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  • Hisamoto Hideaki
    Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University

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  • 最新のキャピラリー電気泳動とチップ電気泳動　　キャピラリー・アセンブルド・マイクロチップ：角型キャピラリー埋め込みチップに基づく電気泳動分離システムの開発
  • キャピラリー-アセンブルド・マイクロチップ--角型キャピラリー埋め込みチップに基づく電気泳動分離システムの開発
  • キャピラリー アセンブルド マイクロチップ カクガタ キャピラリー ウメコミ チップ ニ モトズク デンキ エイドウ ブンリ システム ノ カイハツ

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Abstract

“Capillary-Assembled Microchip (CAs-CHIP)” is fabricated by embedding the chemically-functionalized square capillaries into lattice polydimethylsiloxane channel having same channel dimensions as the outer dimensions of square capillaries. This new approach of chip fabrication allowed us not only the integration of various chemical functions, but also that of multiphase flow process onto a single microchip. Here we propose two types of different applications of CAs-CHIP for electrophoretic separations. First one is the usage as a pretreatment attachment for capillary electrophoresis separation, and the other is the usage as an “injection cross” structure for microchip capillary electrochromatography using an octadecylsilane-modified square capillary. Preliminary results of these two applications suggested the wide applicability of CAs-CHIP in the field of electrophoretic separations.<br>

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