Active Smoking, Passive Smoking, and Breast Cancer Risk : Findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk

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Author(s)

    • LIN Yingsong
    • Department of Public Health, Aichi Medical University School of Medicine
    • KIKUCHI Shogo
    • Department of Public Health, Aichi Medical University School of Medicine
    • TAMAKOSHI Koji
    • Department of Public Health, Nagoya University Graduate School of Medicine
    • WAKAI Kenji
    • Department of Preventive Medicine/Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine
    • KONDO Takaaki
    • Department of Medical Technology, Nagoya University School of Health Sciences
    • NIWA Yoshimitsu
    • Department of Preventive Medicine/Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine
    • YATSUYA Hiroshi
    • Department of Public Health, Nagoya University Graduate School of Medicine
    • NISHIO Kazuko
    • Department of Preventive Medicine/Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine
    • SUZUKI Sadao
    • Department of Health Promotion and Disease Prevention, Nagoya City University Graduate School of Medicine
    • TOKUDOME Shinkan
    • Department of Health Promotion and Disease Prevention, Nagoya City University Graduate School of Medicine
    • YAMAMOTO Akio
    • Infectious Diseases Division, Hyogo Prefectural Institute of Public Health and Environmental Sciences
    • MORI Mitsuru
    • Department of Public Health, Sapporo Medical University School of Medicine
    • TAMAKOSHI Akiko
    • Department of Public Health, Aichi Medical University School of Medicine

Abstract

<B>Background:</B> Evidence is lacking regarding the relationship between cigarette smoking and breast cancer in Japanese women. We examined the association between breast cancer incidence and active and passive smoking in the Japan Collaborative Cohort Study for Evaluation of Cancer Risk.<BR><B>Methods:</B> Our study comprised 34,401 women aged 40-79 years who had not been diagnosed previously with breast cancer and who provided information on smoking status at baseline (1988-1990). The subjects were followed from enrollment until December 31, 2001. Cox proportional-hazards models were used to estimate the hazard ratio (HR) and 95% confidence interval (CI) for the association between breast cancer incidence and tobacco smoke.<BR><B>Results:</B> During 271,412 person-years of follow-up, we identified 208 incident cases of breast cancer. Active smoking did not increase the risk of breast cancer, with a HR for current smokers of 0.67 (95% CI: 0.32-1.38). Furthermore, an increased risk of breast cancer was not observed in current smokers who smoked a greater number of cigarettes each day. Overall, passive smoking at home or in public spaces was also not associated with an increased risk of breast cancer among nonsmokers. Women who reported passive smoking during childhood had a statistically insignificant increase in risk (HR: 1.24; 95% CI: 0.84-1.85), compared with those who had not been exposed during this time.<BR><B>Conclusion:</B> Smoking may not be associated with an increased risk of breast cancer in this cohort of Japanese women.

Journal

  • Journal of Epidemiology

    Journal of Epidemiology 18(2), 77-83, 2008-03-01

    Japan Epidemiological Association

References:  28

Codes

  • NII Article ID (NAID)
    10024796102
  • NII NACSIS-CAT ID (NCID)
    AA10952696
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    09175040
  • DOI
    10.2188/jea.18.77
  • Data Source
    CJP  J-STAGE 
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