Histocompatibility Assessment in the Chicken Colonies of the RIR-Y8/NU, YL, WL-G, and BL-E Closed for 28-48 Years
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- VALDEZ Jr. Marcos B.
- Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University
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- KINOSHITA Keiji
- Avian Bioscience Research Center, Graduate School of Bioagricultural Sciences, Nagoya University
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- MIZUTANI Makoto
- Avian Bioscience Research Center, Graduate School of Bioagricultural Sciences, Nagoya University
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- FUJIWARA Akira
- Laboratory Animal Research Station, Nippon Institute for Biological Science
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- YAZAWA Hajime
- Laboratory Animal Research Station, Nippon Institute for Biological Science
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- YAMAGATA Takahiro
- Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University
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- SHIMADA Kiyoshi
- Avian Bioscience Research Center, Graduate School of Bioagricultural Sciences, Nagoya University
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- NAMIKAWA Takao
- Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University Avian Bioscience Research Center, Graduate School of Bioagricultural Sciences, Nagoya University
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Histocompatibility was assessed in the RIR-Y8/NU, BL-E, YL, and WL-G chicken closed colonies by hemagglutination test using anti-red blood cell (RBC) antibodies (HT), skin transplantation test (STT), and formation of isohemagglutinins (FIHs) during STT. The YL individuals all showed the survival of skingrafts for more than 17 days with no FIHs in STT and no RBC antigenic variations in HT, indicating a histocompatible nature together with high homogeneity at serological loci. The BL-E as well as WL-G closed colonies were also found to be histocompatible in the STT with no FIHs, although the HT showed heterogeneities at serological locus/loci other than the B and C blood group loci which have significant effects on histocompatibility or FIHs in chicken. In the RIR-Y8/NU closed colonies, one individual in 6 reciprocal combinations of the STT showed early skingraft rejection with positive FIHs caused by different B locus alleles, and the HT suggested relatively high heterogeneities at the other serological loci too. The closed colonies of YL, BL-E, and WL-G will be useful avian materials for transplantation or related experiments, but RIR-Y8/NU needs further pedigree selection for serological homogeneity.<br>
収録刊行物
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- Experimental Animals
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Experimental Animals 58 (2), 169-174, 2009
公益社団法人 日本実験動物学会
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詳細情報 詳細情報について
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- CRID
- 1390001205045000448
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- NII論文ID
- 10024838378
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- NII書誌ID
- AA11032321
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- ISSN
- 18817122
- 00075124
- 13411357
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- NDL書誌ID
- 10206617
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- 使用不可