Lactobacillus plantarum No. 14 株の抗アレルギー効果  [in Japanese] Lactobacillus plantarum Strain No. 14 Suppresses Human Allergic Reaction  [in Japanese]

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Abstract

<I>Lactobacillus plantarum</I> No. 14株を被験者28人に二重盲検法により摂取させ,そのスギ花粉症に対する効果を調べた.実施期間は2005年1~3月とし,No. 14株の凍結乾燥菌体を1日2.0×10<SUP>10</SUP>CFU, 3週間連続摂取させた.その結果,血液成分において群間に有意な差はなかったが,No. 14株摂取により総IgEの有意な減少が見られた.また摂取を終了した後でも総IgE, 好酸球数の上昇を抑制した.アレルギー症状に関しては鼻回数が摂取3週間目と後観察1週目で試験群がプラセボ群に対して有意に少なくなった.また,体脂肪率が摂取前後でプラセボ群は有意に上昇したのに対し,試験群は有意に減少した.このことからNo. 14株の摂取により花粉症が抑制され,体脂肪率が低減する可能性が示唆された.

We conducted a placebo-controlled, double blind study to evaluate the effects of <I>Lactobacillus plantarum</I> strain No. 14 (No. 14) on the Japanese cedar pollen allergy. The study was carried out between January and March 2005 during the Japanese cedar pollination season. A total of 28 female students were given 0.5 g (2.0×10<SUP>10</SUP>CFU) of No. 14 for 3 weeks. We observed no significant differences in blood constituents between the placebo and No. 14 groups. However, the total serum IgE level significantly decreased due to No. 14 intake. After the 3-week duration, increases in the total serum IgE level and the eosinophil counts were also observed in the placebo group, but were suppressed in the No.14 group. The occurrence of the subjective symptom (a runny nose) was significantly less for the No. 14 group than for the placebo group between week 1 and week 3. Moreover, percent body fat was significantly decreased after No. 14 intake. These results show that a daily oral intake of No. 14 suppresses Japanese cedar pollinosis and decreases percent body fat.

Journal

  • Nippon Shokuhin Kagaku Kogaku Kaishi

    Nippon Shokuhin Kagaku Kogaku Kaishi 55(12), 625-631, 2008-12-15

    Japanese Society for Food Science and Technology

References:  11

Cited by:  8

Codes

  • NII Article ID (NAID)
    10024854771
  • NII NACSIS-CAT ID (NCID)
    AN10467499
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    1341027X
  • NDL Article ID
    9735952
  • NDL Source Classification
    ZP34(科学技術--食品工学・工業)
  • NDL Call No.
    Z17-126
  • Data Source
    CJP  CJPref  NDL  J-STAGE  JASI 
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