Organometallic Chemistry in [NiFe] Hydrogenases: Synthesis of the Structural and Functional Models

• Matsumoto Tsuyoshi

• Ohki Yasuhiro

• Tatsumi Kazuyuki

  Research Center for Materials Science, Nagoya University

Bibliographic Information

Other Title

• [NiFe]ヒドロゲナーゼの有機金属化学：活性部位の構築と機能モデル
• 〔NiFe〕ヒドロゲナーゼの有機金属化学:活性部位の構築と機能モデル
• NiFe ヒドロゲナーゼ ノ ユウキ キンゾク カガク カッセイ ブイ ノ コウチク ト キノウ モデル

Abstract

Hydrogenases catalyze reversible oxidation/reduction of molecular-hydrogen/protons in nature, and the enzymes are classified into three groups, namely, the [NiFe], [FeFe], and [Fe] hydrogenases. We herein summarize our structural and functional model studies on the [NiFe] hydrogenase. A seires of (OC)₃Fe(II)-Ni(II), (OC)₂(NC)₂Fe(II)-Ni(II), and (OC)(NC)₂Fe(II)-Ni(II) complexes bridged by thiolato ligands have been synthesized as models of the [NiFe] hydrogenase active site. The investigations of dihydrogen activation at the chalcogenido bridged Ge-Ru and W-Ru complexes, and coordinatively unsaturated Ir and Rh thiolato complexes provide clues to understand the mechanism of the [NiFe] hydrogenase function.

Journal

• Journal of Synthetic Organic Chemistry, Japan

  Journal of Synthetic Organic Chemistry, Japan 67 (5), 540-553, 2009

  The Society of Synthetic Organic Chemistry, Japan

Keywords

• [NiFe] hydrogenase
• dihydrogen activation
• heterolysis of dihydrogen
• chalcogenide
• thiolate
• hetero-dinuclear complex
• μ-hydride
• H-D exchange
• coordinative unsaturation
• concerto catalysis

Details

• CRID: 1390001205313195520
• NII Article ID: 10024969046
• NII Book ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.67.540
• COI: 1:CAS:528:DC%2BD1MXmtFKrsr0%3D
• ISSN: 18836526
• ISSN: 00379980
• NDL BIB ID: 10306369
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10306369
• Web Site: https://www.jstage.jst.go.jp/article/yukigoseikyokaishi/67/5/67_5_540/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed