Synthesis of Several Types of Bridged Nucleic Acids

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Author(s)

    • RAHMAN S. M. Abdur
    • Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka
    • IMANISHI Takeshi
    • Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka
    • OBIKA Satoshi
    • Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka

Abstract

A number of bridged nucleic acids with conformationally locked sugar moiety were synthesized from the readily accessible sugar derivatives. The conformations of the sugar moiety of the bridged nucleic acids (BNAs) are locked to either N-type or S-type sugar puckering. This article summarizes the synthesis of these nucleic acid analogues.

Journal

  • Chemistry Letters

    Chemistry Letters 38(6), 512-517, 2009-06-05

    The Chemical Society of Japan

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Codes

  • NII Article ID (NAID)
    10025122435
  • NII NACSIS-CAT ID (NCID)
    AA00603318
  • Text Lang
    ENG
  • Article Type
    REV
  • ISSN
    03667022
  • Data Source
    CJP  J-STAGE 
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