生体分子の細胞内動態を解析する分子科学

• 小澤 岳昌

  東京大学大学院理学系研究科

書誌事項

タイトル別名

• Molecular Science for Analyzing Dynamics of Biomolecules in Living Cells
• セイタイ ブンシ ノ サイボウナイ ドウタイ オ カイセキスル ブンシ カガク

抄録

Developments in methodological and technological aspects for biomolecular imaging are highly expected. We developed a novel design of split GFP and split luciferase; the principle is based on reconstitution of the split-reporter fragments when they are brought sufficiently close together. The usefulness of the split-reporter reconstitution has been demonstrated such as imaging of endogenous mRNA, protease activities, protein-protein interactions and protein transport into a specific organelle. This review introduces the basic principle of the reconstitution technology and its wider application in the fields of biology and basic medicine.

収録刊行物

• 日本コンピュータ外科学会誌

  日本コンピュータ外科学会誌 10 (4), 489-493, 2008

  THE JAPAN SOCIETY OF COMPUTER AIDED SURGERY

キーワード

• Luciferase
• Imaging
• Protein-Protein Interaction
• Caspase

詳細情報

• CRID: 1390001205390844672
• NII論文ID: 130004256805
• NII論文ID: 10025166192
• NII書誌ID: AN1044100X
• DOI: 10.5759/jscas1999.10.489
• ISSN: 18845770
• ISSN: 13349486
• ISSN: 13449486
• NDL書誌ID: 10185041
• Web Site: http://id.ndl.go.jp/bib/10185041
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10185041
• Web Site: https://search.jamas.or.jp/link/ui/2009129775
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• 抄録ライセンスフラグ: 使用不可