Analysis on long-term prognosis of idiopathic membranoproliferative glomerulonephritis in Japanese children
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- Matsumura Chieko
- Department of Pediatrics, Chiba-East National Hospital
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- Kurayama Hideaki
- Department of Pediatrics, Chiba-East National Hospital
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- Kitamura Hiroshi
- Division of Renal Pathology, Clinical Research Center, Chiba-East National Hospital
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- Kanemoto Katsuyoshi
- Department of Pediatrics, Chiba-East National Hospital
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- Anzai Michiko
- Department of Pediatrics, Chiba-East National Hospital
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- Tobita Naomi
- Department of Pediatrics, Chiba-East National Hospital
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- Udagawa Junko
- Children's Forest Clinic
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- Joh Kensuke
- Children's Forest Clinic
Bibliographic Information
- Other Title
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- 小児期発症膜性増殖性腎炎の長期予後についての検討
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Abstract
We investigated a long-term prognosis of 60 children with idiopathic membranoproliferative glomerulonephritis (MPGN) from 1973 to 2006; 50 patients had type I MPGN, 7 dense deposit disease and 3 type III MPGN. Forty-eight children had asymptomatic onset; 46 were identified by school urinary screening program; 40 (83%) had normal urinalysis, normal renal function and histopathological improvement at the last observation. Early detection and treatment was effective for a long-term prognosis. Twelve patients had symptomatic onset; at the last observation, 5 had urinary abnormalities, among which, 4 had nephrotic syndrome (NS) at the onset, and progressed to the end-stage renal failure. NS and frequent crescents formation at the onset associated with a poor prognosis in patients with symptomatic onset.
Journal
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- Japanese journal of pediatric nephrology
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Japanese journal of pediatric nephrology 21 (2), 100-105, 2008
The Japanese Society for Pediatric Nephrology
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Keywords
Details 詳細情報について
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- CRID
- 1390001204338298496
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- NII Article ID
- 10025170301
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- NII Book ID
- AN10328470
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- ISSN
- 18813933
- 09152245
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed