A malignant pancreatic neuro-endocrine tumor with intraductal growth within the main pancreatic duct and tumor thrombus within the splenic vein

DOI 2 Citations 45 References
  • ETO Kazunori
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • KAWAKAMI Hiroshi
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • KUWATANI Masaki
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • HABA Shin
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • HIRANO Satoshi
    Department of Surgical Oncology, Hokkaido University Graduate School of Medicine
  • KONDO Satoshi
    Department of Surgical Oncology, Hokkaido University Graduate School of Medicine
  • KUBOTA Kanako
    Department of Surgical Pathology, Hokkaido University Hospital
  • MATUNO Yoshihiro
    Department of Surgical Pathology, Hokkaido University Hospital
  • HIRAYAMA Atushi
    Department of Digestive Organs, Sapporo-Kosei General Hospital
  • GOTOUDA Yuuko
    Department of Pathology, Sapporo-Kosei General Hospital
  • ASAKA Masahiro
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine

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Other Title
  • 著明な膵管内発育と逆行性門脈内発育による脾内進展を呈した膵内分泌腫瘍の１例

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Abstract

A 71-year-old woman with ischemic colitis was admitted to our hospital for evaluation of a pancreatic tail tumor with splenic infiltration. Endoscopic ultrasonography revealed a heterogenous hypoechoic mass with an irregular, central echogenic area in the tail of the pancreas and a solitary hypoechoic mass within the lumen of the main pancreatic duct(MPD). Endoscopic retrograde pancreatography showed interruption of the MPD in the head of the pancreas. Biopsy of this lesion confirmed a pancreatic neuro-endocrine tumor(NET). A NET with intraductal growth into the MPD and splenic infiltration was diagnosed. The patient underwent curative surgery. Histopathological examination revealed the malignant NET with intraductal growth within the MPD and tumor thrombus within the splenic vein. The patient received no postoperative adjunctive chemotherapy and 11 months after surgery she is alive without recurrence.<br>

Journal

  • Suizo

    Suizo 24 (4), 537-547, 2009

    Japan Pancreas Society

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