Design and Fabrication of Biosensor Device by Use of Receptor Proteins

Access this Article

Search this Article

Author(s)

Abstract

We have been studying a new type of biosensor that uses and mimics sensory functions of insects. The biosensor can be characterized in combination with immobilized signal transduction biomolecules, i.e., receptor proteins, and a semiconductor device as a transducer. We have developed a lipid bilayer membrane for receptor immobilization and combined it with an insulated-gate field-effect transistor (IGFET). By using this bilayer-IGFET device, we have measured changes in the bilayer membrane potential after introducing α-hemolysin, which acts as a model of receptors. This indicates that the developed device could be used for the biosensor using receptor proteins.

Journal

  • IEEJ Transactions on Sensors and Micromachines

    IEEJ Transactions on Sensors and Micromachines 129(10), 317-320, 2009-10-01

    The Institute of Electrical Engineers of Japan

References:  15

Codes

  • NII Article ID (NAID)
    10025318981
  • NII NACSIS-CAT ID (NCID)
    AN1052634X
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    13418939
  • NDL Article ID
    10451106
  • NDL Source Classification
    ZN31(科学技術--電気工学・電気機械工業)
  • NDL Call No.
    Z16-B380
  • Data Source
    CJP  NDL  J-STAGE 
Page Top