Dimethoxy Triazine Glycosides as New Glycosyl Donors for Chemo-enzymatic Synthesis of Oligosaccharides

• Tanaka Tomonari

  Graduate School of Engineering, Tohoku University

• Kobayashi Atsushi

  Graduate School of Engineering, Tohoku University

• Noguchi Masato

  Graduate School of Engineering, Tohoku University

• Kimura Kei-ichi

  Graduate School of Engineering, Tohoku University

• Watanabe Kazuhito

  Graduate School of Engineering, Tohoku University

• Shoda Shin-ichiro

  Graduate School of Engineering, Tohoku University

Bibliographic Information

Other Title

• ヒドロキシ基の保護を必要としない新規糖供与体の一段階合成

Abstract

Various 4-(4,6-dimethoxy-1,3,5-triazin-2-yl) glycosides (DMT-glycosides) have been synthesized from the corresponding free sugars in water by using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride (DMT-MM) as a dehydrative condensing agent. The resulting DMT-glycosides were found to be recognized as substrates for glycosyl hydrolases and could be utilized as novel glycosyl donors for chemo-enzymatic glycosylations. DMT-glycosides will be efficient and general glycosyl donors for glycosidase-catalyzed transglycosylation reaction in the field of carbohydrate chemistry.

Journal

• Journal of Applied Glycoscience

  Journal of Applied Glycoscience 56 (2), 83-88, 2009

  The Japanese Society of Applied Glycoscience

Keywords

• transglycosylation
• glycosidase
• activated glycosyl donor
• one-step preparation
• aqueous solution

Details

• CRID: 1390001206292316160
• NII Article ID: 10025408944
• NII Book ID: AN10453916
• DOI: 10.5458/jag.56.83
• COI: 1:CAS:528:DC%2BD1MXhtFeltLzF
• ISSN: 18807291
• ISSN: 13447882
• NDL BIB ID: 10430699
• Web Site: https://agriknowledge.affrc.go.jp/RN/2010780957
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10430699
• Web Site: http://www.jstage.jst.go.jp/article/jag/56/2/56_2_83/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed