Molecular resolution imaging of protein molecules in liquid using frequency modulation atomic force microscopy

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Abstract

金沢大学フロンティアサイエンス機構

We demonstrated molecular resolution imaging of biological samples such as bacteriorhodopsin protein molecules in purple membrane and isolated chaperonin (GroEL) protein molecules, both adsorbed on mica using frequency modulation atomic force microscope (FM-AFM) in liquid. We also showed that the frequency noise of FM-AFM in liquid can be greatly reduced by the reduction of the noise-equivalent deflection of an optical beam deflection sensor. © 2009 The Japan Society of Applied Physics.

Journal

  • Applied Physics Express

    Applied Physics Express 2 (9), 95007-, 2009-09-01

    Japan Society of Applied Physics = 応用物理学会

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