磁性ナノ粒子を用いた細胞内加温法による温熱療法

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タイトル別名
  • Intracellular Hyperthermia Using Magnetic Nanoparticles: A Novel Method for Hyperthermia Clinical Applications

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抄録

Magnetic nanoparticle-mediated intracellular hyperthermia has been a largely experimental modality of hyperthermia, but this treatment modality has the potential to achieve tumor targeted heating without any side effects. The technique consists of targeting magnetic nanoparticles to tumor tissue and then applying an external alternating magnetic field to induce heat generation by the magnetic nanoparticles. Among available magnetic nanoparticles, magnetite has been extensively studied. Recent years have seen remarkable advances in magnetite nanoparticle-mediated hyperthermia ; both functional magnetite nanoparticles and alternating magnetic field generators have been developed. Currently, some researchers are attempting to begin clinical trials, suggesting that time may have come for clinical applications. This review describes recent advances in magnetite nanoparticle-mediated hyperthermia.

収録刊行物

  • Thermal Medicine

    Thermal Medicine 24 (4), 113-129, 2008

    日本ハイパーサーミア学会

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