New Topics in Vasopressin Receptors and Approach to Novel Drugs : Involvement of Vasopressin V1a and V1b Receptors in Nociceptive Responses and Morphine-Induced Effects

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Author(s)

Abstract

Arginine vasopressin (AVP) receptors have been classified into V1a, V1b, and V2 subtypes. Recent studies have demonstrated the involvement of AVP in anti-nociception and in morphine-induced anti-nociception. However, the roles of individual AVP-receptor subtypes have not been fully elucidated. Here, we have summarized the role of V1-receptor subtypes in behavioral responses to noxious stimuli and to morphine. In this review, we focus on studies using mice lacking the V1a receptor (V1a<sup>−/−</sup> mice) and the V1b receptor (V1b<sup>−/−</sup> mice).<br>

Journal

  • Journal of Pharmacological Sciences

    Journal of Pharmacological Sciences 109(1), 38-43, 2009-01-20

    The Japanese Pharmacological Society

References:  60

Cited by:  1

Codes

  • NII Article ID (NAID)
    10025733490
  • NII NACSIS-CAT ID (NCID)
    AA11806667
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13478613
  • NDL Article ID
    9773059
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z53-D199
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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