Metabolic Syndrome Mortality in a Population-Based Cohort Study : Jichi Medical School (JMS) Cohort Study
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- NIWA Yasunori
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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- ISHIKAWA Shizukiyo
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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- GOTOH Tadao
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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- KAYABA Kazunori
- School of Health and Social Services, Saitama Prefectural University
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- NAKAMURA Yosikazu
- Department of Public Health, Jichi Medical University
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- KAJII Eiji
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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Author(s)
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- NIWA Yasunori
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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- ISHIKAWA Shizukiyo
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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- GOTOH Tadao
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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- KAYABA Kazunori
- School of Health and Social Services, Saitama Prefectural University
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- NAKAMURA Yosikazu
- Department of Public Health, Jichi Medical University
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- KAJII Eiji
- Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
Abstract
<b>BACKGROUND:</b> Metabolic syndrome is known to increase morbidity and mortality of cardiovascular disease. The National Cholesterol Education Program Adult Treatment Expert Panel III in 2001 (revised in 2005) and the Japanese definition of metabolic syndrome were launched in 2005. No study regarding the association between metabolic syndrome by Japanese definition and mortality has been performed. The aim of this study was to clarify the prevalence of metabolic syndrome and its effects to mortality in a population-based cohort study.<br><b>METHODS:</b> A total of 2176 subjects who satisfied the necessary criteria for metabolic syndrome were examined between 1992 and 1995 as a part of Jichi Medical School Cohort Study by Japanese definition. Cox's proportional hazard models were used to analyze the association of metabolic syndrome with mortality.<br><b>RESULTS:</b> The prevalence of metabolic syndrome was 9.0% in males and 1.7% in females. There were 17 deaths (14 males), including 6 cardiovascular deaths (5 males), during a 12.5-year follow-up period among metabolic syndrome subjects. After adjusting for age, smoking status, and alcohol drinking status, the hazard ratio (95% confidence interval) for all-cause mortality was 1.13 (0.64-1.98) in males and 1.31 (0.41-4.18) in females, and HR for cardiovascular mortality was 1.84 (0.68-4.96) in males, and 1.31 (0.17-9.96) in females.<br><b>CONCLUSION:</b> No statistical significant relationship between metabolic syndrome by Japanese definition and all-cause mortality was observed in a population-based cohort study.<br><i>J Epidemiol</i> 2007; 17: 203-209.
Journal
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- Journal of Epidemiology
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Journal of Epidemiology 17(6), 203-209, 2007-11-01
Japan Epidemiological Association
References: 28
-
1
- Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1 : diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
ALBERTI KG
Diabet Med 15, 539-553, 1998
Cited by (1)
-
2
- Banting lecture 1988. Role of insulin resistance in human disease
-
REAVEN GM.
Diabetes 37, 1595-1607, 1988
Cited by (1)
-
3
- Definition and the diagnostic standard for metabolic syndrome-Committee to Evaluate Diagnostic Standards for Metabolic Syndrome
-
Nippon Naika Gakkai Zasshi 94, 794-809, 2005
Cited by (1)
-
4
- The metabolic syndrome : a new worldwide definition
-
ALBERTI KG
Lancet 366, 1059-1062, 2005
Cited by (1)
-
5
- Diagnosis and management of the metabolic syndrome : an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
-
GRUNDY SM
Circulation 112, 2735-2752, 2005
Cited by (1)
-
6
- A proposal for the cutoff point of waist circumference for the diagnosis of metabolic syndrome in the Japanese population
-
HARA K
Diabetes Care 29, 1123-1124, 2006
Cited by (1)
-
7
- Impact of metabolic syndrome on the development of cardiovascular disease in a general Japanese population : the Hisayama study
-
NINOMIYA T
Stroke 38, 2063-2069, 2007
Cited by (1)
-
8
- Metabolic syndrome and the risk of ischemic heart disease and stroke among Japanese men and women
-
ISO H
Stroke 38, 1744-1751, 2007
Cited by (1)
-
9
- Relationship between metabolic risk factor clustering and cardiovascular mortality stratified by high blood glucose and obesity : NIPPON DATA90, 1990-2000
-
KADOTA A
Diabetes Care 30, 1533-1538, 2007
Cited by (1)
-
10
- The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
-
LAKKA HM
JAMA 288, 2709-2716, 2002
Cited by (1)
-
11
- Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women
-
QIAO Q.
Diabetologia 49, 2837-2846, 2006
Cited by (1)
-
12
- Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
-
MALIK S
Circulation 110, 1245-1250, 2004
Cited by (1)
-
13
- The importance of waist circumference in the definition of metabolic syndrome : prospective analyses of mortality in men
-
KATZMARZYK PT
Diabetes Care 29, 404-409, 2006
Cited by (1)
-
14
- Trends in the incidence, mortality, and survival rate of cardiovascular disease in a Japanese community : the Hisayama study
-
KUBO M
Stroke 34, 2349-2354, 2003
Cited by (1)
-
15
- <no title>
-
Health and Welfare Statistics Association
Vital Statistics of Japan 2005 1, 2005
Cited by (1)
-
16
- One-year cardiovascular event rates in outpatients with atherothrombosis
-
STEG PG
JAMA 297, 1197-1206, 2007
Cited by (1)
-
17
- Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)
-
Expert Panel on Detection Evaluation and Treatment of High Blood Choleterol in Adults
JAMA 285, 2486-2497, 2001
Cited by (235)
-
18
- Metabolic Syndrome - Definition and Diagnostic Criteria in Japan
-
MATSUZAWA Yuji
J Atheroscler Thromb 12(6), 301, 2005-12-25
Ichushi Web References (1) Cited by (43)
-
19
- Metabolic Syndrome and Cardiac Disease in Japanese Men : Applicability of the Concept of Metabolic Syndrome Defined by the National Cholesterol Education Program-Adult Treatment Panel III to Japanese Men-The Tanno and Sobetsu Study
-
TAKEUCHI Hiroshi , SAITOH Shigeyuki , TAKAGI Satoru , OHNISHI Hirofumi , OHHATA Junichi , ISOBE Takeshi , SHIMAMOTO Kazuaki
Hypertens Res 28(3), 203-208, 2005-03-01
DOI Ichushi Web References (25) Cited by (84)
-
20
- Prevalence of metabolic syndrome in 22,892 Japanese population and its association with life style
-
URASHIMA M
JMAJ 48, 441-450, 2005
Ichushi Web Cited by (6)
-
21
- Prevalence of Metabolic Syndrome in the General Japanese Population in 2000
-
ARAI Hidenori , YAMAMOTO Akira , MATSUZAWA Yuji , SAITO Yasushi , YAMADA Nobuhiro , OIKAWA Shinichi , MABUCHI Hiroshi , TERAMOTO Tamio , SASAKI Jun , NAKAYA Noriaki , ITAKURA Hiroshige , ISHIKAWA Yuichi , OUCHI Yasuyoshi , HORIBE Hiroshi , SHIRAHASHI Nobuo , KITA Toru
Journal of Atherosclerosis and Thrombosis 13(4), 202-208, 2006-08-31
Ichushi Web References (15) Cited by (35)
-
22
- Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women
-
HU G
Archives of Internal Medicine 164, 1066-1076, 2004
DOI Cited by (10)
-
23
- Japanese Criteria of Metabolic Syndrome
-
Oda Eiji , Watanabe Kenichi
Circulation Journal 70(3), 364-364, 2006
J-STAGE Ichushi Web Cited by (14)
-
24
- Prevalence of Metabolic Syndrome in Okayama Prefecture, Japan
-
Miyatake Nobuyuki , Kawasaki Yuriko , Nishikawa Hidetaka , Takenami Sumiko , Numata Takeyuki
Internal Medicine 45(2), 107-108, 2006
J-STAGE Ichushi Web Cited by (10)
-
25
- Prevalence of the Metabolic Syndrome using the Modified ATP III Definitions for Workers in Japan, Korea and Mongolia
-
SHIWAKU Kuninori , NOGI Akiko , KITAJIMA Keiko , ANUURAD Erdembileg , ENKHMAA Byambaa , YAMASAKI Masayuki , KIM Jung-Man , KIM In-Shik , LEE Sung-Kook , OYUNSUREN Tsendsuren , YAMANE Yosuke
Journal of Occupational Health 47(2), 126-135, 2005-03-01
Ichushi Web References (41) Cited by (10)
-
26
- The Jichi Medical School (JMS) Cohort Study : Design, Baseline Data and Standardized Mortality Ratios
-
ISHIKAWA Shizukiyo , GOTOH Tadao , NAGO Naoki , KAYABA Kazunori , Jichi Medical School (JMS) Cohort Study Group
Journal of Epidemiology 12(6), 408-417, 2002-11
J-STAGE Ichushi Web References (24) Cited by (26)
-
27
- Metabolic Syndrome and C-Reactive Protein in the General Population : JMS Cohort Study
-
ISHIKAWA Shizukiyo , KAYABA Kazunori , GOTOH Tadao , NAKAMURA Yosikazu , KAJII Eiji
Circulation Journal 71(1), 26-31, 2006-12-20
J-STAGE Ichushi Web References (38) Cited by (19)
-
28
- New Criteria for `Obesity Disease' in Japan
-
The Examination Committee of Criteria for `Obesity Disease' in Japan Japan Society for the Study of Obesity
Circulation Journal 66(11), 987-992, 2002-10-20
J-STAGE Ichushi Web References (41) Cited by (170)
Cited by: 5
-
1
- OMEGA Study : Design, Baseline Data, Metabolic Syndrome Prevalence in a Large-Scale Observational Study of Hypertensive Patients : The Olmesartan Mega Study to Determine the Relationship between Cardiovascular Endpoints and Blood Pressure Goal Achievement Study
-
TERAMOTO Tamio , FUJITA Toshiro , KAWAMORI Ryuzo , MIYAZAKI Shigeru , TERAMUKAI Satoshi , IGARASHI Masao
Hypertens Res 31(11), 2011-2017, 2008-11-01
Ichushi Web References (32) Cited by (1)
-
2
- Impact of Metabolic Syndrome Components on the Incidence of Cardiovascular Disease in a General Urban Japanese Population : The Suita Study
-
KOKUBO Yoshihiro , OKAMURA Tomonori , YOSHIMASA Yasunao , MIYAMOTO Yoshihiro , KAWANISHI Katsuyuki , KOTANI Yasushi , OKAYAMA Akira , TOMOIKE Hitonobu
Hypertens Res 31(11), 2027-2035, 2008-11-01
Ichushi Web References (29) Cited by (19)
-
3
- Plasma Adiponectin Level and Myocardial Infarction : the JMS Cohort Study
-
HATANO Yu , MATSUMOTO Masatoshi , ISHIKAWA Shizukiyo , KAJII Eiji
Journal of Epidemiology 19(2), 49-55, 2009-03-01
J-STAGE Ichushi Web References (48)
-
4
- Development of a statistical metabolic syndrome simulator [in Japanese]
-
ZUSHI Makoto , YAMAOKA Kazue , WATANABE Mariko , TANGO Toshiro
Japanese journal of public health 57(12), 1043-1053, 2010-12-15
Ichushi Web References (15)
-
5
- Association Between Stroke and Metabolic Syndrome in a Japanese Population : Jichi Medical School (JMS) Cohort Study
-
NIWA Yasunori , ISHIKAWA Shizukiyo , GOTOH Tadao , KAYABA Kazunori , NAKAMURA Yosikazu , KAJII Eiji
Journal of Epidemiology 20(1), 62-69, 2010-01-01
J-STAGE Ichushi Web References (23) Cited by (3)