Effect of surface roughness on initial responses of osteoblast-like cells on two types of zirconia
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- YAMASHITA Daisuke
- Department of Periodontology, Graduate school of Medical and Dental Sciences, Kagoshima University
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- MACHIGASHIRA Miho
- Department of Periodontology, Graduate school of Medical and Dental Sciences, Kagoshima University
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- MIYAMOTO Motoharu
- Department of Periodontology, Graduate school of Medical and Dental Sciences, Kagoshima University
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- TAKEUCHI Hironobu
- Department of Periodontology, Graduate school of Medical and Dental Sciences, Kagoshima University
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- NOGUCHI Kazuyuki
- Department of Periodontology, Graduate school of Medical and Dental Sciences, Kagoshima University
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- IZUMI Yuichi
- Section of Periodontology, Department of Hard Tissue Engineering, Division of Bio-Matrix, Graduate School, Tokyo Medical and Dental University Global Center of Excellence (GCOE) Program; International Research Center for Molecular Science in Tooth and Bone Diseases
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- BAN Seiji
- Department of Biomaterials Science, Graduate school of Medical and Dental Sciences, Kagoshima University
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The aim of this study was to evaluate the effect of surface roughness on the initial attachment of mouse osteoblast-like cells on ceriastabilized zirconia/alumina nanocomposite (NANOZR) and yttria-stabilized zirconia (3Y-TZP) in comparison to those on pure titanium (Ti) and alumina oxide (AO). Specimens with smooth and rough surfaces were prepared by grinding with diamond paper or by sandblasting, respectively. For four substrates examined, the number of attached cells on the rough surface specimens was significantly higher than that on the smooth surface specimens (p < 0.05). Integrin α5 and β1 expression had a greater increase in rough surface specimens than in smooth surface specimens. Actin cytoskeleton organization was, however, similar for both smooth and rough surface specimens. NANOZR and 3Y-TZP produced good cell attachment, similar to Ti and AO. The overall results demonstrated that NANOZR and 3Y-TZP with rough surface could provide good initial cell responses, adequate for future implant usage.
収録刊行物
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- Dental Materials Journal
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Dental Materials Journal 28 (4), 461-470, 2009
一般社団法人 日本歯科理工学会
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詳細情報 詳細情報について
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- CRID
- 1390282679693746816
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- NII論文ID
- 10025916151
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- NII書誌ID
- AA10443149
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- COI
- 1:CAS:528:DC%2BD1MXht1yjsr%2FJ
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- ISSN
- 18811361
- 02874547
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- PubMed
- 19721284
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可