Immunohistochemical Observation of Heat Shock Proteins Expression in Mouse Periodontal Tissues due to Orthodontic Mechanical Stress
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- Muraoka Rina
- Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
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- Nakano Keisuke
- Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Matsumoto Dental University Institute for Oral Science
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- Matsuda Hirokazu
- Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
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- Tomoda Maki
- Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
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- Okafuji Norimasa
- Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine
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- Kurihara Saburo
- Matsumoto Dental University Institute for Oral Science
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- Yamada Kazuhiro
- Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine
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- Kawakami Toshiyuki
- Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine Matsumoto Dental University Institute for Oral Science
Bibliographic Information
- Other Title
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- 歯科矯正学的メカニカルストレスによりマウス歯根膜組織に発現する熱ショックタンパクの免疫組織化学的観察
- シカ キョウセイガクテキ メカニカルストレス ニ ヨリ マウス シコン マク ソシキ ニ ハツゲン スル ネツ ショックタンパク ノ メンエキ ソシキ カガクテキ カンサツ
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Abstract
Heat shock proteins (HSPs) are induced by not only the heat shock but also the mechanical stress. Orthodontic tooth movement induced mechanical stress in the related periodontal ligament. It is important to examine the immunohistochemical profile change of the Heat shock proteins (HSPs) in the periodontal ligament cells after receiving the mechanical stress for orthodontic treatment. Therefore, we examined the HSPs in the periodontal ligament cells of ddY mice using the Waldo method. In the control group, periodontal ligament was observed as physiological arrangement, and which reacted weakly to HSP27 and HSP70. In the experimental group the extension site of the periodontal ligament cells and the expansion of the blood vessel occurred in the traction side. These tissues were strongly reacted to HSP27 and HSP70. The findings suggeste that the HSPs expression work as the mechanism of maintenance of homeostasis in the periodontal tissues.
Journal
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- Journal of Hard Tissue Biology
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Journal of Hard Tissue Biology 18 (4), 193-198, 2009
THE SOCIETY FOR HARD TISSUE REGENERATIVE BIOLOGY
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Details 詳細情報について
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- CRID
- 1390282679435693184
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- NII Article ID
- 10025928089
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- NII Book ID
- AA11074332
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- ISSN
- 1880828X
- 13417649
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- NDL BIB ID
- 10598198
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed