Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)

• Tsuchihashi-Makaya Miyuki

  Department of Clinical Research and Informatics, Research Institute, International Medical Center of Japan

• Hamaguchi Sanae

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Kinugawa Shintaro

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Yokota Takashi

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Goto Daisuke

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Yokoshiki Hisashi

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Kato Norihiro

  Department of Gene Diagnostics and Therapeutics, Research Institute, International Medical Center of Japan

• Takeshita Akira

  Saiseikai Futsukaichi Hospital

• Tsutsui Hiroyuki

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• for the JCARE-CARD Investigators

書誌事項

タイトル別名

• Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction
• A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)

抄録

Background: Heart failure (HF) with preserved ejection fraction (EF) is common. We compared the characteristics, treatments, and outcomes in HF patients with reduced vs preserved EF by using the national registry database in Japan. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) is a prospective observational study in a broad sample of patients hospitalized with worsening HF. The study enrolled 2,675 patients from 164 hospitals with an average of 2.4 years of follow-up. Patients with preserved EF (EF ≥50% by echocardiography; n=429) were more likely to be older, female, have hypertension and atrial fibrillation, and less likely to have ischemic etiology compared with those with reduced EF (EF <40%; n=985). Unadjusted risk of in-hospital mortality (6.5% vs 3.9%; P=0.03) and post-discharge mortality (22.7% vs 17.8%; P=0.058) was slightly higher in patients with preserved EF, which, however, were not different after multivariable adjustment. Patients with preserved EF had similar rehospitalization rates (36.2% vs 33.4%; P=0.515) compared with patients with reduced EF. Conclusions: HF patients with preserved EF had a similar mortality risk and equally high rates of rehospitalization as those with reduced EF. Effective management strategies are critically needed to be established for this type of HF. (Circ J 2009; 73: 1893-1900)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 73 (10), 1893-1900, 2009

  一般社団法人 日本循環器学会

キーワード

• Ejection fraction
• Heart failure
• Mortality
• Outcome
• Rehospitalization

詳細情報

• CRID: 1390001205102519808
• NII論文ID: 10025936205
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-09-0254
• ISSN: 13474820
• ISSN: 13469843
• Web Site: http://www.jstage.jst.go.jp/article/circj/73/10/73_CJ-09-0254/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2010070616
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可