Double-Blind and Placebo-Controlled Study of the Effectiveness and Safety of Extracorporeal Cardiac Shock Wave Therapy for Severe Angina Pectoris

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Author(s)

    • KIKUCHI Yoku
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • ITO Kenta
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • ITO Yoshitaka
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • SHIROTO Takashi
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • TSUBURAYA Ryuji
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • AIZAWA Kentaro
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • HAO Kiyotaka
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • FUKUMOTO Yoshihiro
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • TAKAHASHI Jun
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • TAKEDA Morihiko
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • NAKAYAMA Masaharu
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • YASUDA Satoshi
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • KURIYAMA Shinichi
    • Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
    • TSUJI Ichiro
    • Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
    • SHIMOKAWA Hiroaki
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine

Abstract

<b><i>Background:</i></b> Low-energy shock wave (SW) therapy has improved myocardial ischemia in both a porcine model and in patients with severe angina pectoris. <b><i>Methods and Results:</i></b> To further confirm the effectiveness and safety of SW therapy, 8 patients with severe angina pectoris were treated with SW therapy in a double-blind, placebo-controlled and cross-over manner. SW therapy, but not placebo, significantly improved chest pain symptoms and cardiac function without any complications or adverse effects. <b><i>Conclusions:</i></b> Extracorporeal cardiac SW therapy is an effective, safe and non-invasive therapeutic option for severe angina pectoris. (<i>Circ J</i> 2010; <b>74:</b> 589 - 591)<br>

Journal

  • Circulation Journal

    Circulation Journal 74(3), 589-591, 2010-02-25

    The Japanese Circulation Society

References:  15

Cited by:  3

Codes

  • NII Article ID (NAID)
    10025943921
  • NII NACSIS-CAT ID (NCID)
    AA11591968
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13469843
  • Data Source
    CJP  CJPref  J-STAGE 
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