Double-Blind and Placebo-Controlled Study of the Effectiveness and Safety of Extracorporeal Cardiac Shock Wave Therapy for Severe Angina Pectoris

DOI Web Site PubMed 被引用文献19件 参考文献25件
  • Kikuchi Yoku
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Ito Kenta
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Ito Yoshitaka
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Shiroto Takashi
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Tsuburaya Ryuji
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Aizawa Kentaro
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Hao Kiyotaka
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Fukumoto Yoshihiro
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Takahashi Jun
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Takeda Morihiko
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Nakayama Masaharu
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Yasuda Satoshi
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Kuriyama Shinichi
    Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
  • Tsuji Ichiro
    Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
  • Shimokawa Hiroaki
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine

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Background: Low-energy shock wave (SW) therapy has improved myocardial ischemia in both a porcine model and in patients with severe angina pectoris. Methods and Results: To further confirm the effectiveness and safety of SW therapy, 8 patients with severe angina pectoris were treated with SW therapy in a double-blind, placebo-controlled and cross-over manner. SW therapy, but not placebo, significantly improved chest pain symptoms and cardiac function without any complications or adverse effects. Conclusions: Extracorporeal cardiac SW therapy is an effective, safe and non-invasive therapeutic option for severe angina pectoris. (Circ J 2010; 74: 589 - 591)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 74 (3), 589-591, 2010

    一般社団法人 日本循環器学会

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