自律神経異常の関与 Involvement of autonomic disorders

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著者

    • 青木 光広 AOKI Mitsuhiro
    • 岐阜大学大学院医学系研究科耳鼻咽喉科学分野 Department of Otolaryngology, Gifu University Graduate School of Medicine

抄録

Patients with orthostatic dysregulation (OD)-associated disease may show autonomic disorders more frequently as compared with patients with other types of dizziness. However, the pathological mechanisms of OD remain unclear. We examined the cardiovascular autonomic function in dizzy patients with postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) in order to evaluate the contribution of the autonomic disorders to the occurrence of dizziness. Heart rate variability analysis during the Schellong test showed that patients with POTS have hypo-parasympathetic function and relative hyper-sympathetic function, and that some patients with OI also have hypo-parasympathetic function. In our clinic, single therapy with a β1-blocker (Atenolol) for patients with POTS or single therapy with an a- agonist for patients with OI relieved orthostatic symptoms in 60% of the patients with POTS and OI. Further clinical studies on OD-associated disease to evaluate methods for accurate diagnosis and appropriate combined physical and pharmacotherapy may improve the outcomes in patients with OD-associated disease.

収録刊行物

  • Equilibrium research

    Equilibrium research 67(3), 234-241, 2008-06-01

    一般社団法人 日本めまい平衡医学会

参考文献:  11件中 1-11件 を表示

被引用文献:  1件中 1-1件 を表示

各種コード

  • NII論文ID(NAID)
    10026087538
  • NII書誌ID(NCID)
    AN00001485
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    03855716
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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