Comparison of the Effects on Meniere's Symptoms and Medication Compliance between Isosorbid-liquid and Isosorbid-jelly

• Miyabe Junji

  Department of Otolaryngology, Osaka University, School of Medicine

• Kitahara Tadashi

  Department of Otolaryngology, Osaka University, School of Medicine

• Horii Arata

  Department of Otolaryngology, Osaka University, School of Medicine

• Maekawa Chie

  Department of Otolaryngology, Osaka University, School of Medicine

• Kizawa Kaoru

  Department of Otolaryngology, Osaka University, School of Medicine

• Kubo Takeshi

  Department of Otolaryngology, Osaka University, School of Medicine

Bibliographic Information

Other Title

• メニエール病に対するイソソルビド液状とゼリー状の治療効果と服薬コンプライアンスの比較検討

Abstract

Most patients with Meniere's disease can be successfully treated with medication. In Japan, since the 1980's we have usually used osmotic diuretics, such as Isosorbide-liquid to control the inner ear endolymphatic hydrops. We have, however, had problems in that Meniere's patients sometimes complain of the tough regimen involving taking Isosorbide-liquid on a daily basis. Recently, Isosorbide-jelly has been developed to improve the medication compliance for patients with Meniere's disease. In the present study, we examined differences between the effects of Isosorbide-liquid and Isosorbide-jelly on hearing and vertigo. We also compared the medication compliance of Isosorbide-liquid with that of Isosorbide-jelly. There were no significant differences in hearing level and vertigo frequency in Meniere's patients before and after Isosorbide-liquid was changed to Isosorbide-jelly. Regarding medication compliance, we should consider which Isosorbide-type we use for each patient on an individual basis.

Journal

• Equilibrium Research

  Equilibrium Research 67 (4), 307-310, 2008

  Japan Society for Equilibrium Research

Keywords

• Meniere's disease
• osmotic diuretics
• isosorbid-liquid
• isosorbid-jelly
• medication compliance

Details

• CRID: 1390282679927658624
• NII Article ID: 10026087742
• NII Book ID: AN00001485
• DOI: 10.3757/jser.67.307
• ISSN: 1882577X
• ISSN: 03855716
• Web Site: https://search.jamas.or.jp/link/ui/2008320691
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed