Waiting-for-Instruction Behavior as Depressive Symptom in Mentally Retarded Autistic Children and Adolescents and Its Treatment

• Yokoyama Hiroyuki

  Devision of Clinical Nursing, Yamagata University School of Nursing Department of Pediatrics, Tohoku University School of Medicine

• Hirose Mieko

  Department of Pediatrics, Tohoku University School of Medicine

• Nara Chieko

  Department of Pediatrics, Tohoku University School of Medicine

• Wakusawa Keisuke

  Department of Pediatrics, Tohoku University School of Medicine

• Kubota Yuki

  Department of Pediatrics, Tohoku University School of Medicine

• Haginoya Kazuhiro

  Takuto Rehabilitation Center for Children

• Tsuchiya Shigeru

  東北大学大学院医学系研究科発生・発達医学講座小児病態学分野

• Iinuma Kazuie

  Ishinomaki Red Cross Hospital

Bibliographic Information

Other Title

• 知的障害を伴う自閉症児 (者) の抑うつ症状としての「指示待ち」と治療的介入

Abstract

  We have seen 9 moderately to severely mentally-retarded autistic children and adolescents who waited for small-step instructions to perform previously acquired daily life activities (called “waiting-for-instruction” behavior). None of these patients were capable of expressing their depressive mood. All cases were considered to meet the criteria for major depressive episode described in DSM-IV. The “waiting-for-instruction” behavior was suggested to be a diagnostic key for depressive state in mentally retarded children and adolescents. GAF scales for depressive symptoms including the “waiting-for-instruction” behavior improved in 7 of these 9 cases with fluvoxamine. Risperidone and valproate sodium were useful for these symptoms in patients who were not responsive to fluvoxamine. Therefore, there is a possibility that they met the criteria for bipolar II disorder in DSM-IV.

Journal

• NO TO HATTATSU

  NO TO HATTATSU 41 (6), 431-435, 2009

  The Japanese Society of Child Neurology

Keywords

• 指示待ち
• 気分障害
• 知的障害
• 抑うつ状態
• 自閉症

Details

• CRID: 1390001205519399424
• NII Article ID: 10026133190
• NII Book ID: AN0020232X
• DOI: 10.11251/ojjscn.41.431
• ISSN: 18847668
• ISSN: 00290831
• Web Site: https://search.jamas.or.jp/link/ui/2010097777
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed