Physical Activity and All-cause Mortality in Japan: The Jichi Medical School (JMS) Cohort Study

  • Hayasaka Shinya
    Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine
  • Shibata Yosuke
    Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine
  • Ishikawa Shizukiyo
    Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
  • Kayaba Kazunori
    School of Health and Social Services, Saitama Prefectural University
  • Gotoh Tadao
    Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
  • Noda Tatsuya
    Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine
  • Murata Chiyoe
    Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine
  • Yamada Tomoyo
    Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine
  • Goto Yasuaki
    Japan Health and Research Institute
  • Nakamura Yosikazu
    Department of Public Health, Jichi Medical University
  • Ojima Toshiyuki
    Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine

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Background: In April 2008, a new health check-up and health guidance system was introduced by the Japanese Government to promote increased physical activity. However, few studies have documented the health benefits of physical activity in Asian populations. We examined the association between all-cause mortality and level of physical activity in a Japanese multicommunity population-based study.<BR>Methods: The Jichi Medical School Cohort Study is a multicommunity, population-based study based in 12 districts in Japan. Baseline data from 4222 men and 6609 women (mean age, 54.8 and 55.0 years, respectively) were collected between April 1992 and July 1995. The participants were followed for a mean duration of 11.9 years. To determine the association between all-cause mortality and level of physical activity, crude mortality rates per 1000 person-years and hazard ratios (HRs) with 95% confidence intervals (CI) were determined using the Cox proportional hazards model. Physical activity was categorized by using physical activity index (PAI) quartiles. The lowest (first) PAI quartile was defined as the HR reference.<BR>Results: In men, the lowest mortality rate was observed in the third quartile, with 95 deaths and a crude mortality rate of 7.6; the age- and area-adjusted HR was 0.59 (95% CI, 0.45–0.76), and the mortality curve had a reverse J shape. In women, the lowest mortality rate was observed in the highest PAI quartile, with 69 deaths and a crude mortality rate of 3.5; the HR was 0.81 (95% CI, 0.58–1.12).<BR>Conclusion: Our results suggest that increased physical activity lowers the risk for all-cause death in Japanese.

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