糖尿病患者における食品の摂取順序による食後血糖上昇抑制効果  [in Japanese] Crossover Study of the Effect of "Vegetables Before Carbohydrates" on Reducing Postprandial Glucose and Insulin in Japanese Subjects with Type 2 Diabetes Mellitus  [in Japanese]

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Author(s)

    • 今井 佐恵子 IMAI Saeko
    • 大阪府立大学総合リハビリテーション学部栄養療法学専攻 Department of Clinical Nutrition, Faculty of Comprehensive Rehabilitation, Osaka Prefecture University
    • 松田 美久子 MATSUDA Mikuko
    • 大阪府立大学総合リハビリテーション学部栄養療法学専攻 Department of Clinical Nutrition, Faculty of Comprehensive Rehabilitation, Osaka Prefecture University
    • 藤本 さおり [他] FUJIMOTO Saori
    • 大阪府立大学総合リハビリテーション学部栄養療法学専攻 Department of Clinical Nutrition, Faculty of Comprehensive Rehabilitation, Osaka Prefecture University
    • 宮谷 秀一 MIYATANI Shuichi
    • 大阪府立大学総合リハビリテーション学部栄養療法学専攻 Department of Clinical Nutrition, Faculty of Comprehensive Rehabilitation, Osaka Prefecture University
    • 長谷川 剛二 HASEGAWA Goji
    • 京都府立医科大学内分泌糖尿病内科 Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
    • 福井 道明 FUKUI Michiaki
    • 京都府立医科大学内分泌糖尿病内科 Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
    • 小笹 寧子 OZASA Neiko
    • 京都大学医学部付属病院循環器内科 Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine

Abstract

2型糖尿病患者を対象に,野菜を米飯の後に摂取した場合と米飯の前に摂取した場合の,摂取後の血糖値および血清インスリン値を無作為クロスオーバー法により調べた.野菜から先に摂取すると,米飯から先に摂取した場合と比較して,30分後の血糖値は217±40 mg/d<i>l</i>から172±31 mg/d<i>l</i>(<i>p</i><0.01),60分後は208±56 mg/d<i>l</i>から187±41 mg/d<i>l</i>と低値を示した.インスリン値も30分後,60分後共に有意に抑制された.「食べる順番」を重視した容易な教育方法が食事指導に重要であると考える.<br>

Postprandial hyperglycemia is associated with increased risk for macrovascular disease. We studied the effects of eating "vegetables before carbohydrates" on postprandial plasma glucose in outpatients with type 2 diabetes mellitus (T2DM). We conducted a randomized crossover study in 15 subjects with T2DM patients controlled by diet and having the following profiles age 61.7±11.6 yrs, male/female ratio: 7/8, BMI 24.7±4.3, HbA<sub>1c</sub> 6.0±0.6%, years of DM duration 5.3±8.8 yrs: mean±SD. Subjects ate test meals consisting of white rice and vegetable salad, eating either "carbohydrates before vegetables" or vice versa for 4 weeks. Plasma glucose and serum insulin were evaluated at 0, 30, 60, and 120 min after each meal. Postprandial plasma glucose in those following the "vegetables before carbohydrates" regimen was reduced at 30 and 60 min compared to the reverse regimen at 217±40 vs 172±31 mg/d<i>l</i> (<i>P</i><0.01) and 208±56 vs 187±41 mg/d<i>l</i> (<i>P</i>=0.074). Postprandial serum insulin decreased significantly at 30 and 60 min in the "vegetables before rice" regimen at 32.9±20.8 vs 22.3±14.6 <i>μ</i>U/m<i>l</i> (<i>P</i><0.01), 35.4±21.6 vs 24.9±13.4<i>μ</i>U/m<i>l</i> (<i>P</i><0.05). These results suggest that eating vegetables before carbohydrates may be beneficial in preventing subjects with postprandial hyperglycemia and T2DM.<br>

Journal

  • Journal of the Japan Diabetes Society

    Journal of the Japan Diabetes Society 53(2), 112-115, 2010-02-28

    THE JAPAN DIABETES SOCIETY

References:  9

Cited by:  5

Codes

  • NII Article ID (NAID)
    10026317599
  • NII NACSIS-CAT ID (NCID)
    AN00166576
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    0021437X
  • NDL Article ID
    10605738
  • NDL Source Classification
    ZS21(科学技術--医学--内科学)
  • NDL Call No.
    Z19-401
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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