SRD Young Investigator Award 2009: Nitric oxide and luteal blood flow in the luteolytic cascade in the cow

DOI 機関リポジトリ Web Site Web Site 参考文献87件
  • SHIRASUNA Koumei
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine

書誌事項

タイトル別名
  • Nitric Oxide and Luteal Blood Flow in the Luteolytic Cascade in the Cow

この論文をさがす

抄録

The corpus luteum (CL) of the estrous cycle in the cow is a dynamic organ which has a lifespan of approximately 17-18 days. The main function of the CL is to produce progesterone (P) that requires for achievement and maintenance of pregnancy. If pregnancy does not occur successfully, the CL must regress within a few days to induce the next chance of ovulation. As the CL matures, the steroidogenic cells establish contact with many capillary vessels, consequently the CL is composed of a large number of vascular endothelial cells that can account for up to 50% of all cells. Therefore, blood vessels and blood flow within the CL have an essential role in luteal function. Nitric oxide (NO), a strong vasorelaxant, is now known to play key roles in a variety of physiological process. Indeed, NO has established itself as a polyvalent molecule which plays a decisive role in regulating multiple functions within female reproductive system. In the CL, NO is produced and regulates luteal blood flow, P secretion and apoptosis of luteal cells as well as endothelial cells. This review describes the current investigation for possible roles of NO in the luteolytic cascade within the bovine CL.<br>

収録刊行物

参考文献 (87)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ