Three Cases of Vesiculo-bullous Lesions of the Gingiva with Effectiveness of Exfoliative Cytology

DOI 26 References
  • KUYAMA Kayo
    Department of Oral Pathology, Nihon University School of Dentistry at Matsudo
  • ENDO Hiroyasu
    Department of Periodontology, Nihon University School of Dentistry at Matsudo
  • NAKADAI Mami
    Department of Oral and Maxillofacial Implantology, Nihon University School of Dentistry at Matsudo
  • F. FIFITA Sisilia
    Department of Oral Pathology, Nihon University School of Dentistry at Matsudo
  • SUN Yan
    Department of Oral Pathology, Nihon University School of Dentistry at Matsudo
  • KATO Takao
    Department of Oral and Maxillofacial Implantology, Nihon University School of Dentistry at Matsudo
  • YAMAMOTO Hirotsugu
    Department of Oral Pathology, Nihon University School of Dentistry at Matsudo

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  • 剥離細胞診が有用であった歯肉に発症した水疱性疾患の3例

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Abstract

Oral exfoliative cytology is one of simple examination methods in which cells are scraped from the surface of oral lesions observed under a microscope. The present report of 3 cases describes the patients showing the gingival diseases with vesiculobullous lesions that were presumptively diagnosed by exfoliative cytology. All 3 patients complained of painful and erythematous gingivae. Smears were obtained by brushing the attached gingiva using a cytobrush. Tzanck cells, which were demonstrated two-ton colored cytoplasm; eosinophilic in nuclear surroundings and light-blue in periphery of cytoplasm, were observed in 2 cases. Therefore, the possibility of pemphigus vulgaris was suspected. Cells where virus infection was suggested, those were demonstrated nuclear ground glass appearance and multi-nucleated; each nucleus was face to face with another squeezed together, were observed during the therapeutic process with applying topical corticosteroid in one of the same 2 cases, and additionally in another one case. Thus, the exfoliative cytology was useful in screening for herpes virus infection or pemphigus vulgaris on the gingival lesions in these 3 cases.

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