本邦におけるエナメル上皮腫の病態と治療法に関する疫学的研究  [in Japanese] Epidemiological study of characteristics and treatments of ameloblastoma in Japan  [in Japanese]

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Author(s)

    • 森田 章介 MORITA Shosuke
    • 大阪歯科大学口腔外科学第一講座 First Department of Oral and Maxillofacial Surgery, Osaka Dental University
    • 杉原 一正 SUGIHARA Kazumasa
    • 鹿児島大学大学院医歯学総合研究科顎顔面機能再建学講座顎顔面疾患制御学分野 Department of Maxillofacial Diagnostic and Surgical Science Field of Oral and Maxillofacial Rehabilitation Kagoshima University Graduate School of Dental and Medical Sciences
    • 山口 朗 YAMAGUCHI Akira
    • 東京医科歯科大学大学院口腔機能再建学講座口腔病理学分野 Section of Oral Pathology, Department of Oral Restitution, Graduate School of Tokyo Medical and Dental University

Abstract

1995年1月から2004年12月の10年間に本学会評議員が所属する61施設で,エナメル上皮腫と診断,治療された947症例に対してアンケートによる疫学的調査を実施した。性別は男性581例,女性366例であり,年代別にみると男性は20歳代で18.6%とピークを示し,女性では10歳代で23.2%とピークを示した。また部位では臼歯部が最も多く55.6%であった。臨床症状では疼痛が46.6%と最も多く,次いで腫脹が13.6%であった。エックス線所見は単房性が50.7%,多房性が40.4%であった。2005年のWHO歯原性腫瘍組織分類ではsolid/multicystic typeが74.5%と最も多く,次いでunicystic typeが17.0%,desmoplastic typeが4.1%,extraosseous/peripheral typeが3.0%であった。治療法では,顎骨保存療法(開窓145例15.9%,摘出開放創187例20.5%,摘出・掻爬289例31.8%を含む)が74.0%,顎骨切除療法が24.1%であった。

We studied 947 patients with ameloblastoma who visited and were treated at the 61 institutions certified as training facilities by the Japan Society for Oral Tumors between 1995 and 2004. Ameloblastoma were reclassified according to the new WHO classification revised in 2005 and the clinicopathological data were analyzed. The patients were 581 males and 366 females. The higher age groups were 20s (18.6%) in male and 10s in female (23.2%). The most frequent and affected location was the molar region (55.6%). The frequent clinical findings were pain (46.6%) and swelling (13.6%). Radiographically, unilocular appearance was observed in 50.7 %, multilocular appearance was seen in 40.4%. Histopathologically, solid/multicystic type was observed in 74.5%, unicystic type in 17.0%, desmoplastic type in 4.1%, and extraosseous/peripheral type in 3.0%. The treatment modalities for ameloblastomas were both conservative surgery (74.0%) and radical ones (24.1%).

Journal

  • Journal of Japanese Society of Oral Oncology

    Journal of Japanese Society of Oral Oncology 21(3), 171-181, 2009-09-15

    Japanese Society of Oral Oncology

References:  28

Cited by:  7

Codes

  • NII Article ID (NAID)
    10026399587
  • NII NACSIS-CAT ID (NCID)
    AN10170059
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    09155988
  • Data Source
    CJP  CJPref  J-STAGE 
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